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Table 1 Characteristics of the study cohort (n = 238,963) at baseline

From: Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database

Characteristic n %a
Sex
 Male 92,935 (38.9)
 Female 146,028 (61.1)
Mean age (SD) 39.5 (11.1)
Ethnic group recorded 136,624 (57.2)
Ethnic group:
 White/not recorded 227,451 (95.2)
 Non-white 11,512 (4.8)
Depression severity (index diagnosis):
 Mild 171,208 (71.7)
 Moderate 59,140 (24.8)
 Severe 8615 (3.6)
Smoking statusb:
 Recorded 233,290 (97.6)
 Non smoker 110,849 (47.5)
 Ex-smoker 35,132 (15.1)
 Current light smoker 24,104 (10.3)
 Current moderate smoker 40,546 (17.4)
 Current heavy smoker 22,659 (9.7)
Alcohol consumptionb:   
 Recorded 203,189 (85.0)
 Non drinker 55,253 (27.2)
 Trivial (less than 1 unit per day) 77,579 (38.2)
 Light (1–2 units per day) 51,310 (25.3)
 Moderate (3–6 units per day) 14,482 (7.1)
 Heavy (7–9 units per day) 2174 (1.1)
 Very heavy (over 9 units per day) 2391 (1.2)
Townsend deprivation score in fifthsb:
 Recorded 230,762 (96.6)
 1 (Least deprived) 45,021 (19.5)
 2 46,207 (20.0)
 3 48,293 (20.9)
 4 47,063 (20.4)
 5 (Most deprived) 44,178 (19.1)
Comorbidities at baseline:
 Any cancer 3810 (1.6)
 Asthma/chronic obstructive airways disease 31,816 (13.3)
 Coronary heart disease 4109 (1.7)
 Diabetes 7371 (3.1)
 Hypertension 17,217 (7.2)
 Stroke/transient ischaemic attack 1741 (0.7)
 Epilepsy/seizures 3325 (1.4)
 Previous falls 4321 (1.8)
 Hypothyroidism 5267 (2.2)
 Obsessive-compulsive disorder 494 (0.2)
 Osteoarthritis 7228 (3.0)
 Osteoporosis 867 (0.4)
 Liver disease 698 (0.3)
 Renal disease 549 (0.2)
 Rheumatoid arthritis 1301 (0.5)
Medications at baseline:
 Anticonvulsants 2672 (1.1)
 Antihypertensive drugs 25,344 (10.6)
 Antipsychotics 836 (0.4)
 Anticoagulants 1073 (0.5)
 Aspirin 7159 (3.0)
 Bisphosphonates 854 (0.4)
 Hypnotics/anxiolytics 11,354 (4.8)
 Non-steroidal anti-inflammatory drugs 12,725 (5.3)
 Statins 10,823 (4.5)
 Oral contraceptivesc 27,396 (18.8)
 Hormone replacement therapyc 7207 (4.9)
  1. aValues are numbers (column percentages) unless stated otherwise
  2. bPercentages for smoking status, alcohol and deprivation are out of total with recorded values
  3. cPercentage is for females only
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