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Table 1 Characteristics of the study cohort (n = 238,963) at baseline

From: Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database

Characteristic

n

%a

Sex

 Male

92,935

(38.9)

 Female

146,028

(61.1)

Mean age (SD)

39.5

(11.1)

Ethnic group recorded

136,624

(57.2)

Ethnic group:

 White/not recorded

227,451

(95.2)

 Non-white

11,512

(4.8)

Depression severity (index diagnosis):

 Mild

171,208

(71.7)

 Moderate

59,140

(24.8)

 Severe

8615

(3.6)

Smoking statusb:

 Recorded

233,290

(97.6)

 Non smoker

110,849

(47.5)

 Ex-smoker

35,132

(15.1)

 Current light smoker

24,104

(10.3)

 Current moderate smoker

40,546

(17.4)

 Current heavy smoker

22,659

(9.7)

Alcohol consumptionb:

  

 Recorded

203,189

(85.0)

 Non drinker

55,253

(27.2)

 Trivial (less than 1 unit per day)

77,579

(38.2)

 Light (1–2 units per day)

51,310

(25.3)

 Moderate (3–6 units per day)

14,482

(7.1)

 Heavy (7–9 units per day)

2174

(1.1)

 Very heavy (over 9 units per day)

2391

(1.2)

Townsend deprivation score in fifthsb:

 Recorded

230,762

(96.6)

 1 (Least deprived)

45,021

(19.5)

 2

46,207

(20.0)

 3

48,293

(20.9)

 4

47,063

(20.4)

 5 (Most deprived)

44,178

(19.1)

Comorbidities at baseline:

 Any cancer

3810

(1.6)

 Asthma/chronic obstructive airways disease

31,816

(13.3)

 Coronary heart disease

4109

(1.7)

 Diabetes

7371

(3.1)

 Hypertension

17,217

(7.2)

 Stroke/transient ischaemic attack

1741

(0.7)

 Epilepsy/seizures

3325

(1.4)

 Previous falls

4321

(1.8)

 Hypothyroidism

5267

(2.2)

 Obsessive-compulsive disorder

494

(0.2)

 Osteoarthritis

7228

(3.0)

 Osteoporosis

867

(0.4)

 Liver disease

698

(0.3)

 Renal disease

549

(0.2)

 Rheumatoid arthritis

1301

(0.5)

Medications at baseline:

 Anticonvulsants

2672

(1.1)

 Antihypertensive drugs

25,344

(10.6)

 Antipsychotics

836

(0.4)

 Anticoagulants

1073

(0.5)

 Aspirin

7159

(3.0)

 Bisphosphonates

854

(0.4)

 Hypnotics/anxiolytics

11,354

(4.8)

 Non-steroidal anti-inflammatory drugs

12,725

(5.3)

 Statins

10,823

(4.5)

 Oral contraceptivesc

27,396

(18.8)

 Hormone replacement therapyc

7207

(4.9)

  1. aValues are numbers (column percentages) unless stated otherwise
  2. bPercentages for smoking status, alcohol and deprivation are out of total with recorded values
  3. cPercentage is for females only