From: Impact of atopy on risk of glioma: a Mendelian randomisation study
Trait | IVW | MLE | WME | MBE | MR-Egger slope | MR-Egger intercept | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | Estimate (95% CI) | P | |
Asthma and hay fever | 0.96 (0.90–1.03) | 0.248 | 0.96 (0.93–1.00) | 0.066 | 0.93 (0.86–1.01) | 0.087 | 0.91 (0.80–1.04) | 0.191 | 0.99 (0.72–1.36) | 0.951 | −0.007 (−0.030 to 0.016) | 0.542 |
Atopic dermatitis | 0.96 (0.93–1.00) | 0.041 | 0.96 (0.94–0.99) | 0.003 | 0.96 (0.91–1.01) | 0.114 | 0.97 (0.92–1.02) | 0.194 | 0.97 (0.92–1.03) | 0.375 | 0.004 (−0.014 to 0.006) | 0.396 |
IgE level | 0.88 (0.69–1.13) | 0.319 | 0.88 (0.74–1.05) | 0.157 | 0.83 (0.61–1.12) | 0.218 | 0.82 (0.57–1.19) | 0.355 | 0.63 (0.32–1.25) | 0.184 | 0.027 (0.001 to 0.053) | 0.042 |
Self-reported allergy | 1.03 (0.95–1.11) | 0.534 | 1.02 (0.97–1.08) | 0.429 | 1.08 (0.97–1.20) | 0.184 | 1.12 (0.92–1.36) | 0.275 | 0.92 (0.69–1.22) | 0.540 | 0.017 (0.003 to 0.031) | 0.018 |