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Table 4 Median child cause-specific chance-corrected concordance (%) for InSilicoVA and Tariff 2.0

From: Performance of InSilicoVA for assigning causes of death to verbal autopsies: multisite validation study using clinical diagnostic gold standards

  

InSilicoVA (Tariff 2.0 training)

Tariff 2.0

  

No HCE

HCE

No HCE

HCE

PHMRC cause

ICD10

Median

95% UI

Median

95% UI

Median

95% UI

Median

95% UI

Diarrhea/dysentery

A09

16.0

(14.1, 18.0)

15.1

(12.5, 16.7)

24.6

(24.0, 25.5)

37.0

(36.3, 38.2)

Sepsis

A41

−2.8

(−5.0, −1.5)

−5.0

(−5.0, −2.7)

12.5

(11.2, 13.5)

14.7

(14.1, 16.0)

Hemorrhagic fever

A99

16.0

(14.5, 19.0)

16.0

(13.6, 19.7)

51.5

(51.5, 52.3)

59.6

(59.6, 65.0)

Measles

B05

73.8

(70.2, 77.2)

71.9

(67.8, 73.8)

82.5

(82.5, 82.5)

82.5

(82.5, 82.5)

AIDS

B24

42.7

(39.1, 47.4)

42.1

(38.2, 47.4)

37.0

(37.0, 37.0)

58.0

(58.0, 58.0)

Malaria

B54

47.5

(47.2, 49.8)

49.3

(47.4, 51.3)

41.7

(40.0, 42.1)

57.2

(56.6, 58.8)

Other infectious diseases

B99

24.8

(22.8, 27.0)

25.0

(21.4, 27.2)

7.4

(7.4, 10.0)

26.5

(25.9, 27.8)

Other cancers

C76

4.3

(−2.8, 6.2)

5.0

(1.8, 8.0)

25.0

(25.0, 30.0)

40.0

(40.0, 40.0)

Meningitis

G03

15.0

(12.5, 16.4)

13.3

(11.9, 15.5)

27.3

(25.0, 32.5)

30.0

(26.5, 32.5)

Encephalitis

G04

29.9

(26.5, 32.2)

29.8

(24.8, 33.0)

37.0

(37.0, 37.0)

41.7

(37.0, 47.5)

Other cardiovascular diseases

I99

7.7

(6.1, 10.4)

10.8

(8.9, 13.9)

11.6

(11.6, 12.5)

33.7

(33.7, 33.7)

Pneumonia

J22

16.8

(15.6, 18.3)

16.0

(14.4, 17.5)

7.7

(7.1, 8.1)

9.9

(9.1, 10.8)

Other digestive diseases

K92

4.0

(2.4, 5.5)

4.2

(2.3, 6.7)

3.8

(3.8, 3.8)

21.3

(21.3, 21.3)

Other defined causes of child deaths

R101

13.0

(11.2, 14.5)

11.2

(8.8, 12.3)

5.5

(4.5, 6.2)

16.9

(16.0, 18.3)

Road traffic

V89

90.1

(88.8, 91.2)

89.5

(88.3, 91.2)

90.5

(88.9, 90.9)

90.9

(90.9, 92.5)

Falls

W19

54.6

(51.7, 57.6)

55.9

(52.9, 57.9)

73.8

(73.8, 73.8)

73.8

(73.8, 73.8)

Drowning

W74

92.5

(90.7, 93.6)

92.5

(91.2, 94.1)

90.0

(89.5, 90.0)

93.8

(92.5, 94.8)

Fires

X09

50.9

(47.5, 52.9)

48.4

(47.4, 52.2)

69.1

(69.1, 69.1)

75.3

(73.8, 75.3)

Bite of venomous animal

X27

88.5

(86.8, 90.4)

87.7

(85.6, 89.5)

92.5

(92.5, 92.5)

92.5

(92.5, 100.0)

Poisonings

X49

37.1

(30.0, 42.3)

40.0

(34.4, 45.3)

47.5

(47.5, 47.5)

73.8

(73.8, 73.8)

Violent death

Y09

75.3

(73.7, 76.8)

76.6

(73.7, 79.0)

83.8

(82.5, 83.8)

83.8

(83.8, 83.8)

  1. Table 4 shows the cause-specific chance-corrected concordance for child data for InSilicoVA using an empirical probbase derived from training data mapped to the Tariff 2.0 format. Previously published Tariff 2.0 results are shown for comparison
  2. PHMRC Population Health Metrics Research Consortium, ICD International Classification of Diseases, HCE health care experience, UI uncertainty interval