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Table 4 Subgroup analysis

From: Clinical trial registration and reporting: a survey of academic organizations in the United States

  CTSA affiliation Cancer center affiliationa Account size Total
QUESTION (number of participants who viewed question) CTSA (N = 109) Not CTSA (N = 257) Cancer center (N = 97) Not cancer center (N = 267) ≥ 100 records (N = 98) 20–99 records (N = 77) < 20 reords (N = 191) (N = 366)
Number of records 29,076 11,275 24,970 14,940 35,269 3756 1326 40,351
Does the organization have a registration policy? (N = 366)
 Yes 58 53% 98 38% 61 63% 94 35% 63 64% 33 43% 60 31% 156 43%
 No 40 37% 133 52% 30 31% 142 53% 29 30% 39 51% 105 55% 173 47%
 Don’t know 11 10% 26 10% 6 6% 31 12% 6 6% 5 6% 26 14% 37 10%
Does the organization have a results reporting policy? (N = 366)
 Yes 52 48% 77 30% 52 54% 77 28% 55 56% 26 34% 48 25% 129 35%
 No 46 42% 147 57% 37 38% 154 58% 36 37% 44 57% 113 59% 193 53%
 Don’t know 11 10% 33 13% 8 8% 36 14% 7 7% 7 9% 30 16% 44 12%
Does the organization have an electronic system for managing trial registration or results reporting? (N = 366)
 Yes 27 25% 41 16% 26 27% 41 15% 26 27% 7 9% 35 18% 68 19%
 No 73 67% 199 77% 68 70% 203 76% 68 69% 66 86% 138 72% 272 74%
 Don’t know 9 8% 17 7% 3 3% 23 9% 18 18% 4 5% 4 2% 26 7%
Number of full-time equivalent (FTE) staff (N = 288)b N = 94
Mean (SD) =
0.59 (0.83)
N = 193
Mean (SD) =
0. 17 (0.39)
N = 84
Mean (SD) =
0.56 (0.81)
N = 201
Mean (SD) =
0.25 (0.72)
N = 88
Mean (SD) =
0.69 (0.83)
N = 61
Mean (SD) =
0.13 (0.24)
N = 138
Mean (SD) =
0.14 (0.41)
N = 287
Mean (SD) =
0.31 (0.60)
Median (IQR) =
0.25 (0.05 to 0.95)
Median (IQR) =
0.05 (0.02 to 0.15)
Median (IQR) =
0.25 (0.05 to 0.85)
Median (IQR) =
0.05 (0.02 to 0.15)
Median (IQR) =
0.42 (0.15 to 1.00)
Median (IQR) =
0.06 (0.02 to 0.15)
Median (IQR) =
0.05 (0.01 to 0.10)
Median (IQR) =
0.08 (0.02 to 0.25)
Range
0 to 5.6
Range
0 to 4
Range
0 to 5.6
Range
0 to 4
Range
0 to 5.6
Range
0 to 1.58
Range
0 to 4
Range
0 to 5.6
  1. CTSA Accounts affiliated with a Clinical and Translational Science Award (CTSA). The number of CTSA affiliated accounts exceeds the number of CTSAs because multiple accounts were sometimes affiliated with the same CTSA. Not CTSA Accounts not affiliated with a CTSA. Cancer center Accounts affiliated with a National Cancer Institute (NCI) cancer center or another cancer center. Not cancer center Accounts not affiliated with an NCI or other cancer center. ≥ 100 records Accounts with 100 or more registered studies in the USA for which the organization was listed as the “lead sponsor.” 20–99 records Accounts with between 20 and 99 registered studies. < 20 records Accounts with fewer than 20 registered studies
  2. aTwo accounts did not report whether they are affiliated with a cancer center; they are not included in this subgroup analysis
  3. bResults are for accounts that responded to this question. In our initial analysis, we found potentially invalid data; for example, some participants entered “0.5” rather than “50%”. This occurred because a software bug prevented us from enforcing a data validation rule in the survey. To verify these results, we emailed administrators who indicated that staff spent ≤ 1% of their time on trial registration and reporting. Post hoc, we excluded two outliers because they appeared to report the total number of staff employed at the organization rather than the number of staff who support trial registration and results reporting