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Table 3 Quality assessment of included non-randomised controlled trials

From: Efficacy and safety of methylene blue in the treatment of malaria: a systematic review

Methodological item Score for studiesa
Bountogo et al.
Burkina Faso
(2010) [59]
Meissner et al.
Burkina Faso
(2006) [60]
Alving (1949)
Cited by Baird et al. (2012) [61]
Clearly stated aim 2 2 1
Inclusion of consecutive patients 2 2 1
Prospective collection of data 2 2 0
End points appropriate to the aim of the study 1 2 1
Unbiased assessment of the study end point 2 2 0
Follow-up period appropriate to the aim of the study 2 2 1
Loss to follow-up less than 5% 2 2 0
Prospective calculation of the study size 2 2 0
Adequate control group 1 2 1
Contemporary groups 1 1 1
Baseline equivalence of groups 1 2 0
Adequate statistical analyses 2 2 0
Total score 20 23 6
  1. aThe items are scored 0 (not reported), 1 (reported but inadequate) or 2 (reported and adequate). The global ideal score was 24 for comparative studies