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Table 2 Comparison of mean value and standard deviation (SD) of CD4/CD8 ratio, CD8, and CD4 at switch and 12 months after switch between triple and dual and between triple and monotherapy

From: Switching to dual/monotherapy determines an increase in CD8+ in HIV-infected individuals: an observational cohort study

  Triple (N = 1073) Dual (N = 104) p value Mono (N = 64) p value
CD4/CD8 ratio
 At switch, mean (SD) 0.76 (0.46) 0.85 (0.51) 0.054 0.89 (0.50) 0.009
 12 months after switch, mean (SD) 0.88 (0.63) 0.89 (0.52) 0.666 0.97 (0.55) 0.091
  Change, mean (SD) +0.12 (0.48) +0.04 (0.15) 0.004 +0.07 (0.21) 0.079
CD8 cell count
 At switch, mean (SD) 912 (454) 924 (504) 0.778 825 (345) 0.220
 12 months after switch, mean (SD) 884 (506) 986 (558) 0.197 860 (410) 0.576
  Change, mean (SD) −28 (471) +62 (321) 0.010 +34 (222) 0.096
CD4 cell count
 At switch, mean (SD) 588 (289) 652 (320) 0.039 646 (260) 0.022
 12 months after switch, mean (SD) 654 (294) 738 (338) 0.012 705 (223) 0.017
  Change, mean (SD) +66 (184) +86 (180) 0.251 +59 (197) 0.757