Table 2 Comparison of mean value and standard deviation (SD) of CD4/CD8 ratio, CD8, and CD4 at switch and 12 months after switch between triple and dual and between triple and monotherapy
Triple (N = 1073) | Dual (N = 104) | p value | Mono (N = 64) | p value | |
|---|---|---|---|---|---|
CD4/CD8 ratio | |||||
At switch, mean (SD) | 0.76 (0.46) | 0.85 (0.51) | 0.054 | 0.89 (0.50) | 0.009 |
12 months after switch, mean (SD) | 0.88 (0.63) | 0.89 (0.52) | 0.666 | 0.97 (0.55) | 0.091 |
Change, mean (SD) | +0.12 (0.48) | +0.04 (0.15) | 0.004 | +0.07 (0.21) | 0.079 |
CD8 cell count | |||||
At switch, mean (SD) | 912 (454) | 924 (504) | 0.778 | 825 (345) | 0.220 |
12 months after switch, mean (SD) | 884 (506) | 986 (558) | 0.197 | 860 (410) | 0.576 |
Change, mean (SD) | −28 (471) | +62 (321) | 0.010 | +34 (222) | 0.096 |
CD4 cell count | |||||
At switch, mean (SD) | 588 (289) | 652 (320) | 0.039 | 646 (260) | 0.022 |
12 months after switch, mean (SD) | 654 (294) | 738 (338) | 0.012 | 705 (223) | 0.017 |
Change, mean (SD) | +66 (184) | +86 (180) | 0.251 | +59 (197) | 0.757 |