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Table 3 Comparison of mean value and standard deviation (SD) of CD4/CD8 ratio, CD8, and CD4 at switch and 24 months after switch between triple and dual and between triple and monotherapy in two different regimens in 724 patients who had available data at 24 months

From: Switching to dual/monotherapy determines an increase in CD8+ in HIV-infected individuals: an observational cohort study

  Triple (N = 622) Dual (N = 57) p value Mono (N = 45) p value
CD4/CD8 ratio
 At switch, mean (SD) 0.76 (0.45) 0.80 (0.37) 0.167 0.90 (0.48) 0.025
 24 months after switch, mean (SD) 0.93 (0.71) 0.88 (0.43) 0.824 1.02 (0.50) 0.105
  Change, mean (SD) +0.17 (0.58) +0.08 (0.19) 0.024 +0.12 (0.22) 0.786
CD8 cell count
 At switch, mean (SD) 912 (458) 882 (471) 0.396 812 (363) 0.173
 24 months after switch, mean (SD) 867 (451) 911 (411) 0.337 913 (575) 0.870
  Change, mean (SD) −45 (401) +28 (256) 0.017 +101 (404) 0.012
CD4 cell count
 At switch, mean (SD) 588 (285) 614 (269) 0.402 654 (274) 0.040
 24 months after switch, mean (SD) 683 (294) 703 (272) 0.285 795 (332) 0.006
  Change, mean (SD) +95 (181) +89 (175) 0.943 +141 (229) 0.205