Table 3 Comparison of mean value and standard deviation (SD) of CD4/CD8 ratio, CD8, and CD4 at switch and 24 months after switch between triple and dual and between triple and monotherapy in two different regimens in 724 patients who had available data at 24 months
Triple (N = 622) | Dual (N = 57) | p value | Mono (N = 45) | p value | |
|---|---|---|---|---|---|
CD4/CD8 ratio | |||||
At switch, mean (SD) | 0.76 (0.45) | 0.80 (0.37) | 0.167 | 0.90 (0.48) | 0.025 |
24 months after switch, mean (SD) | 0.93 (0.71) | 0.88 (0.43) | 0.824 | 1.02 (0.50) | 0.105 |
Change, mean (SD) | +0.17 (0.58) | +0.08 (0.19) | 0.024 | +0.12 (0.22) | 0.786 |
CD8 cell count | |||||
At switch, mean (SD) | 912 (458) | 882 (471) | 0.396 | 812 (363) | 0.173 |
24 months after switch, mean (SD) | 867 (451) | 911 (411) | 0.337 | 913 (575) | 0.870 |
Change, mean (SD) | −45 (401) | +28 (256) | 0.017 | +101 (404) | 0.012 |
CD4 cell count | |||||
At switch, mean (SD) | 588 (285) | 614 (269) | 0.402 | 654 (274) | 0.040 |
24 months after switch, mean (SD) | 683 (294) | 703 (272) | 0.285 | 795 (332) | 0.006 |
Change, mean (SD) | +95 (181) | +89 (175) | 0.943 | +141 (229) | 0.205 |