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Table 2 Division of AIDS (DAIDS) grading of adverse event (AE) severity (modified version). This describes the grading system referred to in this study to describe the severity of TB symptoms such as cough, night sweats, weight loss, and hemoptysis

From: Pretreatment chest x-ray severity and its relation to bacterial burden in smear positive pulmonary tuberculosis

Parameter Grade 1 Grade 2 Grade 3 Grade 4
Clinical AE NOT identified elsewhere in this DAIDS AE grading table Symptoms causing no or minimal interference with usual social and functional activities Symptoms causing greater than minimal interference with usual social and functional activities Symptoms causing inability to perform usual social and functional activities Symptoms causing inability to perform basic self-care functions OR Medical or operative intervention indicated to prevent permanent impairment, persistent disability, or death
e.g., Unintentional weight loss NA 5–9% loss in body weight from baseline 10–19% loss in body weight from baseline ≥ 20% loss in body weight from baseline OR aggressive intervention indicated (e.g., tube feeding or total parenteral nutrition)