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Table 1 Participant characteristics by BMI category at the age of 60–64 years

From: Patterns of adiposity, vascular phenotypes and cognitive function in the 1946 British Birth Cohort

 

N

Entire sample

Normal (30.5%)

Overweight (42.5%)

Obese (27.0%)

p value trend

Male sex (%)

1249

46.3

37.0

54.7

43.8

0.046

Height (m)

1249

1.68 (0.1)

1.68 (0.1)

1.69 (0.1)

1.67 (0.1)

0.44

Weight (kg)

1249

78.4 (14.9)

65.3 (8.2)

78.1 (9.2)

94.3 (12.5)

< 0.001

BMI (kg/m2)

1249

27.6 (4.6)

23.0 (1.5)

27.2 (1.4)

33.6 (3.6)

< 0.001

Waist circumference (cm)

1249

96.6 (12.6)

84.6 (8.2)

96.0 (7.6)

109.2 (9.8)

< 0.001

Hip circumference (cm)

1249

105.8 (9.5)

97.7 (4.9)

104.5 (5.1)

115.7 (9.0)

< 0.001

Waist-to-hip ratio

1249

0.91 (0.1)

0.87 (0.1)

0.92 (0.1)

0.95 (0.1)

< 0.001

Heart rate (bpm)

1248

68.4 (11.3)

67.2 (11.4)

68.3 (10.6)

69.8 (12.1)

0.009

SBP (mmHg)

1248

134.8 (17.9)

129.3 (16.7)

136.6 (18.1)

138 (17.9)

< 0.001

DBP (mmHg)

1248

77.2 (9.7)

74.5 (9.4)

78.2 (9.4)

78.7 (10.1)

< 0.001

Education (% above A-level)

909

61.3

61.9

65

54.6

0.14

Smoking (% current smokers)

1171

34.9

37.7

33.7

34.3

0.34

Total cholesterol (mmol/L)

1186

5.69 (1.2)

5.91 (1.1)

5.7 (1.2)

5.4 (1.3)

< 0.001

LDL cholesterol (mmol/L)

1156

3.52 (1.0)

3.66 (0.9)

3.55 (1.0)

3.3 (1.1)

0.001

HDL cholesterol (mmol/L)

1186

1.62 (0.41)

1.81 (0.4)

1.59 (0.4)

1.43 (0.3)

< 0.001

Triglyceridesa (mmol/L)

1162

1.1 (0.8–1.5)

0.8 (0.6–1.1)

1.1 (0.8–1.5)

1.3 (1.0–1.9)

< 0.001

HbA1ca (%)

1157

5.8 (5.5–6)

5.7 (5.5–5.9)

5.7 (5.5–6.0)

5.9 (5.6–6.2)

< 0.001

Adiponectina (μg/mL)

1183

12.9 (7.6–19.5)

16.6 (10.9–25.1)

12.1 (7.0–17.8)

10.2 (6.3–16.4)

< 0.001

Leptina (ng/mL)

1183

12.1 (6.6–23.6)

7.8 (4.1–13.7)

11.6 (6.4–19.1)

26.1 (14.1–43.2)

< 0.001

Levels of physical activity (in the last 4 weeks)

      

• Not physical active

• Moderate

• Intense

1223

703 (58.15)

189 (15.63)

317 (26.22)

205 (54.81)

61 (16.31)

108 (28.88)

297 (58.01)

80 (15.63)

135 (26.37)

201 (62.23)

48 (14.86)

74 (22.91)

0.375

PWV (m/s)

1249

8.2 (1.51)

7.95 (1.58)

8.27 (1.5)

8.37 (1.42)

< 0.001

cIMT (mm)

900

0.69 (0.12)

0.67 (0.12)

0.69 (0.13)

0.71 (0.11)

<0.001

VMT (number of words)

1227

24.7 (6.1)

26.0 (6.0)

24.5 (6.2)

23.6 (5.7)

< 0.001

LSSTa (targets)

1249

282 (231–307)

287 (231–329)

239 (231–329)

263 (174–288)

0.009

S-RT (s)

1234

281 (63.5)

279 (64.5)

278 (60.2)

289 (67.2)

0.038

C-RT (s)

1230

612 (76.5)

607 (77.4)

608 (72.9)

622 (80.6)

0.012

  1. Values are presented as mean ± standard deviation, N (%) or amedian (IQR). Comparisons between normal weight, overweight and obese groups were performed by test for trend using linear regression
  2. Numbers in italic indicate statistical significance
  3. SBP systolic blood pressure, DBP diastolic blood pressure, cIMT common carotid artery intima-media thickness, PWV pulse wave velocity, VMT verbal memory test, LSST letter search speed test, C-RT choice reaction time test, S-RT simple reaction time test
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BMC Medicine

ISSN: 1741-7015

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