Table 1 Details of studies and datasets used for analyses
From: Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation study
Exposure/outcome | Consortium | Participants | Web source if publicly available |
|---|---|---|---|
Serum magnesium | CHARGE and replication studies [22] | 23,829 individuals of European ancestry | Not available |
Coronary artery disease | CARDIoGRAMplusC4D consortium’s 1000 Genomes-based GWAS [23] | 184,305 individuals (60,801 CAD cases and 123,504 non-cases) of mainly European (77%) and Asian (19%) ancestry | |
Blood pressure | ICBP [29] | 69,395 individuals of European ancestry | www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000585.v1.p1 |
Lipids | GLGC [30] | 188,577 individuals of European ancestry | |
Glycaemic traits | MAGIC [31] | 46,186 non-diabetic individuals of European ancestry | |
Body mass index | GIANT [32] | 339,224 individuals of mainly European (95%) ancestry | portals.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium |
Waist-to-hip ratio | GIANT [33] | 224,459 individuals of mainly European (94%) ancestry | portals.broadinstitute.org/collaboration/giant/index.php/GIANT_consortium |
Smoking | TAGC [34] | 74,053 individuals of European ancestry |