Table 3 Search strategy

PubMed

(‘Drug Resistance‘[Mesh] OR Resistance[tiab] OR Resistant[tiab] OR Multiresistant[tiab])

AND

(‘Anti-Bacterial Agents‘[Mesh] OR ‘Macrolides‘[Mesh] OR ‘beta-Lactams‘[Mesh] OR Antibacterial[tiab] OR Antibacterials[tiab] OR Antibiotics[tiab] OR Antibiotic[tiab] OR Macrolides[tiab] OR Macrolide[tiab] OR beta-Lactams[tiab] OR Antimicrobial[tiab] OR Antimicrobials[tiab] OR Penicillin[tiab] OR Methicillin[tiab] OR ampicillin[tiab] OR azithromycin[tiab] OR Cephalexin[tiab])

AND

(‘Population Surveillance‘[Mesh] OR ‘Primary Health Care‘[Mesh] OR ‘Ambulatory Care‘[Mesh] OR ‘Outpatients‘[Mesh] OR ‘Community-Acquired Infections‘[Mesh] OR ‘Demography‘[Mesh] OR ‘Carrier State‘[Mesh] OR ‘Endemic Diseases‘[Mesh] OR ‘Primary care’[tiab] OR ‘Primary healthcare’[tiab] OR ‘Family practice’[tiab] OR ‘General practice’[tiab] OR Ambulatory[tiab] OR Outpatients[tiab] OR Outpatient[tiab] OR Community[tiab] OR Communities[tiab] OR Surveillance[tiab] OR Carrier[tiab] OR Carriage[tiab] OR Area[tiab] OR Areas[tiab] OR Region[tiab] OR Regions[tiab] OR Demographic[tiab])

AND

(‘Drug Prescriptions‘[Mesh] OR ‘Prescriptions‘[Mesh] OR ‘therapeutic use’[sh] OR Prescriptions[tiab] OR Prescription[tiab] OR Prescribing[tiab] OR Prescribe[tiab] OR Prescribed[tiab] OR Consumption[tiab] OR Courses[tiab] OR Course[tiab] OR Programme[tiab] OR Programmes[tiab] OR Dose[tiab] OR Doses[tiab] OR Exposure[tiab] OR Isolates[tiab] OR Isolated[tiab] OR Risk[ti])

AND

(‘Patients‘[Mesh] OR ‘Drug therapy’[sh] OR ‘Drug effects’[sh] OR Microbiology[sh] OR Treatment[tiab] OR Patient[tiab] OR Patients[tiab] OR Patient’s[tiab])

AND

(‘Randomised Controlled Trial’[pt] OR ‘Controlled Clinical Trial’[pt] OR ‘Epidemiologic Studies‘[Mesh] OR Randomly[tiab] OR Randomised[tiab] OR Randomised[tiab] OR Group[tiab] OR Groups[tiab] OR Control[tiab] OR Controlled[tiab] OR Case[tiab] OR Cases[tiab] OR Multicenter OR Center[tiab] OR Centre[tiab] OR Trial[tiab] OR Trials[tiab] OR Compare[tiab] OR Compared[tiab] OR Comparison[tiab] OR Cohort[tiab] OR Observed[tiab] OR Observational[tiab] OR Questionnaires[tiab] OR Questionnaires[tiab] OR Frequency[tiab] OR Frequencies[tiab] OR Baseline[tiab] OR Modelling[tiab])

NOT

(‘Hospitals‘[Mesh] OR ‘Inpatients’[Mesh] OR ‘Cross Infection‘[Mesh] OR Hospitals[ti] OR Hospital[ti] OR Inpatients[tiab] OR Inpatient[tiab] OR ‘Cross infection’[tiab] OR ‘Cross infections’[tiab] OR ‘Hospital acquired’[tiab] OR ‘Hospital infection‘[tiab] OR ‘Hospital infections‘[tiab] OR Animal[tiab] OR Animals[tiab])

NOT

(Review[pt] OR Meta Analysis[pt] OR News[pt] OR Comment[pt] OR Editorial[pt] OR Letter[pt] OR comment on[ti] OR systematic review[ti] or literature review[ti])

NOT

(Animals[Mesh] not (Animals[Mesh] and Humans[Mesh]))

CENTRAL (Cochrane)

([mh ‘Drug Resistance‘] OR Resistance:ti,ab OR Resistant:ti,ab OR Multiresistant:ti,ab)

AND

([mh ‘Anti-Bacterial Agents‘] OR [mh ‘Macrolides‘] OR [mh ‘beta-Lactams‘] OR Antibacterial:ti,ab OR Antibacterials:ti,ab OR Antibiotics:ti,ab OR Antibiotic:ti,ab OR Macrolides:ti,ab OR Macrolide:ti,ab OR beta-Lactams:ti,ab OR Antimicrobial:ti,ab OR Antimicrobials:ti,ab OR Penicillin:ti,ab OR Methicillin:ti,ab OR ampicillin:ti,ab OR azithromycin:ti,ab OR Cephalexin:ti,ab)

AND

([mh ‘Population Surveillance‘] OR [mh ‘Primary Health Care‘] OR [mh ‘Ambulatory Care‘] OR [mh ‘Outpatients‘] OR [mh ‘Community-Acquired Infections‘] OR [mh ‘Demography‘] OR [mh ‘Carrier State‘] OR [mh ‘Endemic Diseases‘] OR ‘Primary care’:ti,ab OR ‘Primary healthcare’:ti,ab OR ‘Family practice’:ti,ab OR ‘General practice’:ti,ab OR Ambulatory:ti,ab OR Outpatients:ti,ab OR Outpatient:ti,ab OR Community:ti,ab OR Communities:ti,ab OR Surveillance:ti,ab OR Carrier:ti,ab OR Carriage:ti,ab OR Area:ti,ab OR Areas:ti,ab OR Region:ti,ab OR Regions:ti,ab OR Demographic:ti,ab)

AND

([mh ‘Drug Prescriptions‘] OR [mh ‘Prescriptions‘] OR ‘therapeutic use‘:kw OR Prescriptions:ti,ab OR Prescription:ti,ab OR Prescribing:ti,ab OR Prescribe:ti,ab OR Prescribed:ti,ab OR Consumption:ti,ab OR Courses:ti,ab OR Course:ti,ab OR Programme:ti,ab OR Programmes:ti,ab OR Dose:ti,ab OR Doses:ti,ab OR Exposure:ti,ab OR Isolates:ti,ab OR Isolated:ti,ab OR Risk:ti)

AND

([mh ‘Patients‘] OR ‘Drug therapy‘:kw OR ‘Drug effects‘:kw OR Microbiology:kw OR Treatment:ti,ab OR Patient:ti,ab OR Patients:ti,ab OR Patient’s:ti,ab)

NOT

([mh ‘Hospitals‘] OR [mh ‘Inpatients‘] OR [mh ‘Cross Infection‘] OR Hospitals:ti OR Hospital:ti OR Inpatients:ti,ab OR Inpatient:ti,ab OR ‘Cross infection‘:ti,ab OR ‘Cross infections‘:ti,ab OR ‘Hospital acquired‘:ti,ab OR ‘Hospital infection‘:ti,ab OR ‘Hospital infections‘:ti,ab OR Animal:ti,ab OR Animals:ti,ab)

NOT

([mh Animals] not ([mh Animals] and [mh Humans]))

EMBASE

(‘Drug Resistance’/exp. OR Resistance:ti,ab OR Resistant:ti,ab OR Multiresistant:ti,ab)

AND

(‘antibiotic agent’/exp. OR ‘Macrolide’/exp. OR ‘beta lactam’/exp. OR Antibacterial:ti,ab OR Antibacterials:ti,ab OR Antibiotics:ti,ab OR Antibiotic:ti,ab OR Macrolides:ti,ab OR Macrolide:ti,ab OR beta-Lactams:ti,ab OR Antimicrobial:ti,ab OR Antimicrobials:ti,ab OR Penicillin:ti,ab OR Methicillin:ti,ab OR ampicillin:ti,ab OR azithromycin:ti,ab OR Cephalexin:ti,ab)

AND

(‘health survey’/exp. OR ‘Primary Health Care’/exp. OR ‘Ambulatory Care’/exp. OR ‘Outpatient’/exp. OR ‘Community-Acquired Infection’/exp. OR ‘Demography’/exp. OR ‘heterozygote’/exp. OR ‘Endemic Disease’/exp. OR ‘Primary care’:ti,ab OR ‘Primary healthcare’:ti,ab OR ‘Family practice’:ti,ab OR ‘General practice’:ti,ab OR Ambulatory:ti,ab OR Outpatients:ti,ab OR Outpatient:ti,ab OR Community:ti,ab OR Communities:ti,ab OR Surveillance:ti,ab OR Carrier:ti,ab OR Carriage:ti,ab OR Area:ti,ab OR Areas:ti,ab OR Region:ti,ab OR Regions:ti,ab OR Demographic:ti,ab)

AND