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Table 4 Detailed reasons for exclusion

From: Resistance decay in individuals after antibiotic exposure in primary care: a systematic review and meta-analysis

Insufficient data reported

No individual patient data reported, reporting only P value

62

No data on the number of resistant isolates

49

No data on the number of patients exposed to antibiotics

47

Time between antibiotic exposure and isolation of resistance not reported

14

Contacted authors and no response received or full text not received (for conference abstracts)

23

Ineligible participant criteria

Hospitalised patients >50% (or hospital-associated infections or inpatients)

89

Patients with persistent infections, device-related infections or tract abnormalities

11

Immunocompromised patients

5

>50% nursing home residents

1

Reporting gene mutations or in vitro resistant isolates

5

Ineligible exposure

Prolonged antibiotic exposure (>2 weeks of exposure)

33

Pharmacokinetics of antibiotic exposure

2

Ineligible outcome data

No before and after outcome data in studies in which all patients received antibiotic treatment

11

Mixed data between resistant and susceptible isolates or all patients have resistant isolates

7

Ineligible study design

Case series, case reports, reviews and reports

8

Duplicates

 

12

Total

 

379