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Table 1 Parameter table. All parameters were estimated using ICHNT data

From: Fast and expensive (PCR) or cheap and slow (culture)? A mathematical modelling study to explore screening for carbapenem resistance in UK hospitals

Parameter

Description

Value

References and notes

CP-CRE prevalence at admission

ICU

1.6% (16/1007)

Calculated from universal screening data of a total of 2870 patients, over a 9-month period

Renal

1.9% (16/858)

Vascular

0.4% (2/541)

Haematology

1.3% (6/464)

Coverage of initial admission screening

ICU

63.0%

Renal

67.0%

Vascular

48.0%

Haematology

68.0%

Number of speciality beds

ICU

112

Sum of all wards in each speciality as in March 2016

Renal

71

Vascular

65

Haematology

66

Length of stay (mean/median)

ICU

S

7.9/4.0

Taken from speciality data and based on initial screening result

CRE

15.9/10.0

Renal

S

7.8/5.0

CRE

15.5/12.0

Vascular

S

6.2/4.0

CRE

12.4/7.0

Haematology

S

9.6/5.0

CRE

19.6/9.0

Time to result (days)

Culture

2

For single component test

PHE PCR

7a

PCR

0.5

(A) Direct PCR

0.5

For complete algorithm

(B) Culture + PCR

2.5

(C) PHE

13

  1. S patient was carrying no Enterobacteriaceae or Enterobacteriaceae susceptible to carbapenems, CRE patient was carrying Enterobacteriaceae resistant to carbapenems. These data come from the patients identified as carriers using the current ICHNT screening procedure
  2. aAccounts for the PHE workload and specimen transportation