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Table 3 Summary of genetic variants used as instrumental variables in summary statistics approach

From: Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study

ID

Gene

Effect allele

Chromosome

Beta (25-OHD)

Se (25-OHD)

Beta (CRC)

Se (CRC)

rs10741657

CYP2R1

A

11

0.0312

0.0022

0.0162

0.0135

rs10745742

AMDHD1

T

12

0.0167

0.0022

−0.0049

0.0138

rs12785878

NADSYN1/ DHCR7

T

11

0.0361

0.0022

−0.0097

0.016

rs17216707

CYP24A1

T

20

0.0262

0.0027

0.0138

0.0173

rs3755967

GC

C

4

0.0893

0.0023

−0.0154

0.0148

rs8018720

SEC23A

G

14

0.0164

0.0029

−0.0163

0.0176

  1. Beta regression coefficients of GWAS meta-analysis, se standard error, CRC colorectal cancer
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BMC Medicine

ISSN: 1741-7015

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