|
Time
|
USA
|
The Netherlands
|
Belgium
|
Norway
|
Slovenia
|
|---|
|
Stages I–II
|
Stages III–IV
|
Stages I–II
|
Stages III–IV
|
Stages I–II
|
Stages III–IV
|
Stages I–II
|
Stages III–IV
|
Stages I–II
|
Stages III–IV
|
|---|
|
OS (95% CI)a
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
OS (95% CI)
|
|---|
|
1 month
|
|
≤ 60 years
|
96 (95–96)
|
77 (76–78)
|
98 (97–99)
|
87 (86–89)
|
98 (97–99)
|
93 (91–95)
|
99 (96–100)
|
92 (90–94)
|
98 (93–99)
|
87 (82–90)
|
|
60–69 years
|
93 (92–93)
|
72 (71–72)
|
96 (95–97)
|
83 (82–84)
|
97 (96–98)
|
89 (87–91)
|
97 (94–98)
|
87 (85–89)
|
97 (92–99)
|
82 (77–86)
|
|
≥ 70 years
|
84 (84–85)
|
60 (59–61)
|
92 (90–93)
|
74 (72–75)
|
93 (92–94)
|
81 (80–83)
|
96 (94–98)
|
80 (78–82)
|
94 (90–97)
|
67 (63–72)
|
|
3 months
|
|
≤ 60 years
|
90 (90–91)
|
59 (58–60)
|
93 (91–94)
|
61 (59–63)
|
95 (93–96)
|
78 (75–80)
|
96 (93–98)
|
67 (63–70)
|
95 (90–98)
|
61 (55–67)
|
|
60–69 years
|
86 (85–87)
|
53 (53–54)
|
89 (87–91)
|
55 (53–57)
|
92 (91–94)
|
69 (67–71)
|
91 (88–94)
|
59 (56–62)
|
93 (88–96)
|
54 (48–59)
|
|
≥ 70 years
|
71 (71–72)
|
40 (39–40)
|
79 (77–81)
|
42 (41–44)
|
83 (81–84)
|
55 (53–56)
|
85 (82–88)
|
44 (42–47)
|
81 (75–86)
|
39 (35–44)
|
|
6 months
|
|
≤ 60 years
|
81 (80–82)
|
41 (40–42)
|
83 (81–86)
|
36 (34–37)
|
90 (87–92)
|
59 (56–62)
|
88 (82–91)
|
43 (39–46)
|
92 (85–95)
|
44 (38–49)
|
|
60–69 years
|
74 (73–75)
|
35 (35–36)
|
79 (77–81)
|
32 (31–34)
|
86 (83–88)
|
50 (48–53)
|
79 (74–83)
|
37 (34–40)
|
82 (74–87)
|
40 (34–45)
|
|
≥ 70 years
|
57 (56–57)
|
24 (24–25)
|
63 (61–66)
|
22 (21–23)
|
67 (65–69)
|
34 (32–35)
|
67 (63–71)
|
22 (20–24)
|
70 (63–76)
|
19 (16–23)
|
|
12 months
|
|
≤ 60 years
|
60 (58–61)
|
20 (20–21)
|
62 (59–65)
|
13 (12–15)
|
72 (69–76)
|
31 (28–34)
|
65 (58–71)
|
20 (17–23)
|
65 (56–72)
|
17 (13–22)
|
|
60–69 years
|
54 (52–55)
|
17 (17–18)
|
57 (54–59)
|
12 (11–13)
|
65 (62–68)
|
24 (22–26)
|
55 (49–60)
|
13 (11–15)
|
59 (50–66)
|
19 (15–24)
|
|
≥ 70 years
|
36 (35–36)
|
10 (10–11)
|
40 (38–42)
|
7 (7–8)
|
43 (40–45)
|
14 (13–15)
|
42 (37–46)
|
7 (6–9)
|
49 (42–56)
|
7 (5–10)
|
|
24 months
|
|
≤ 60 years
|
36 (34–37)
|
7 (6–7)
|
31 (28–34)
|
4 (4–5)
|
47 (43–51)
|
10 (9–12)
|
39 (32–46)
|
7 (5–9)
|
35 (27–43)
|
6 (3–9)
|
|
60–69 years
|
30 (29–31)
|
5 (5–6)
|
30 (27–33)
|
3 (2–3)
|
38 (35–41)
|
6 (4–7)
|
30 (25–35)
|
3 (2–4)
|
24 (18–31)
|
4 (2–6)
|
|
≥ 70 years
|
18 (17–19)
|
3 (3–3)
|
20 (18–22)
|
2 (1–2)
|
21 (19–22)
|
3 (3–4)
|
19 (16–23)
|
2 (1–3)
|
25 (19–31)
|
2 (1–4)
|
|
36 months
|
|
≤ 60 years
|
26 (24–27)
|
3 (3–4)
|
21 (18–24)
|
2 (2–3)
|
34 (30–37)
|
5 (4–7)
|
25 (19–32)
|
4 (2–6)
|
23 (16–30)
|
2 (1–4)
|
|
60–69 years
|
20 (19–21)
|
2 (2–3)
|
19 (17–22)
|
1 (1–2)
|
25 (22–28)
|
2 (1–3)
|
19 (14–24)
|
1 (< 1–2)
|
14 (9–20)
|
2 (1–3)
|
|
≥ 70 years
|
12 (11–12)
|
1 (1–2)
|
14 (12–16)
|
1 (< 1–1)
|
13 (11–14)
|
1 (1–2)
|
13 (10–17)
|
1 (< 1–1)
|
14 (9–19)
|
1 (< 1–2)
|
|
60 months
|
|
≤ 60 years
|
19 (18–20)
|
2 (1–2)
|
14 (12–17)
|
1 (1–1)
|
23 (19–26)
|
2 (1–3)
|
16 (11–22)
|
1 (< 1–2)
|
15 (9–23)
|
2 (1–4)
|
|
60–69 years
|
13 (12–14)
|
1 (1–1)
|
12 (10–14)
|
< 1 (< 1–1)
|
16 (14–19)
|
1 (< 1–1)
|
13 (9–18)
|
< 1 (< 1–1)
|
8 (4–14)
|
1 (< 1–3)
|
|
≥ 70 years
|
7 (7–8)
|
1 (< 1–1)
|
7 (6–9)
|
< 1 (< 1–1)
|
7 (6–8)
|
1 (< 1–1)
|
8 (5–11)
|
< 1 (< 1–1)
|
8 (5–13)
|
< 1 (< 1–1)
|
- OS overall survival, CI confidence interval
- aData are shown as survival proportion (95% confidence interval) [%]
