Survival | Period | Stage | USA | The Netherlands | Belgium | Norway | Slovenia | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Overall | Resected | Overall | Resected | Overall | Resected | Overall | Resected | Overall | Resected | |||
OS (95% CI)a | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | |||
1 month | 2003–2005 | I–II | 83 (82–84) | 95 (94–96) | 89 (87–91) | 96 (93–97) | 94 (92–96) | 97 (94–98) | 91 (88–94) | 99 (94–100) | 89 (84–93) | 96 (90–98) |
III–IV | 61 (60–62) | 86 (82–89) | 73 (71–75) | 88 (74–95) | 88 (85–90) | 96 (86–99) | 78 (75–80) | 100 (100–100) | 69 (65–74) | 92 (71–98) | ||
2006–2008 | I–II | 84 (84–85) | 96 (95–96) | 92 (91–94) | 97 (95–98) | 95 (94–97) | 97 (95–98) | 90 (83–96) | 99 (93–100) | 93 (88–96) | 99 (93–100) | |
III–IV | 62 (61–63) | 89 (86–91) | 77 (75–78) | 100 (100–100) | 86 (85–88) | 98 (91–99) | 79 (76–81) | 96 (75–99) | 75 (71–78) | 97 (80–100) | ||
2009–2011 | I–II | 86 (85–87) | 96 (96–97) | 92 (90–93) | 97 (96–98) | 96 (95–97) | 98 (97–99) | 94 (91–96) | 98 (95–99) | 90 (85–94) | 99 (94–100) | |
III–IV | 63 (62–64) | 90 (88–92) | 76 (75–78) | 91 (81–96) | 85 (84–87) | 100 (100–100) | 78 (75–80) | 96 (77–100) | 75 (72–79) | 98 (86–100) | ||
Percent unit change,b P | I–II | + 3, 0.006 | + 2, 0.004 | + 3, 0.021 | + 1, 0.257 | + 2, 0.116 | + 1, 0.577 | + 3, 0.175 | –1, 0.473 | + 1, 0.851 | + 4, 0.083 | |
III–IV | + 2, 0.002 | + 4, 0.989 | + 3, 0.001 | + 3, 0.635 | –2, 0.086 | +4, 0.189 | + < 1, 0.972 | −4, 0.301 | + 6, 0.024 | + 6, 0.229 | ||
3 months | 2003–2005 | I–II | 72 (71–73) | 91 (90–92) | 74 (71–76) | 92 (89–94) | 86 (83–89) | 93 (90–96) | 76 (71–80) | 98 (93–99) | 76 (69–82) | 87 (79–92) |
III–IV | 42 (41–43) | 74 (69–78) | 42 (40–43) | 84 (69–92) | 66 (62–69) | 93 (82–97) | 44 (41–47) | 87 (68–95) | 36 (31–40) | 58 (36–75) | ||
2006–2008 | I–II | 73 (72–74) | 92 (91–92) | 78 (76–81) | 93 (91–95) | 87 (85–89) | 92 (90–94) | 72 (67–76) | 94 (86–97) | 80 (73–86) | 92 (85–96) | |
III–IV | 44 (43–44) | 79 (76–82) | 46 (44–47) | 98 (88–100) | 63 (61–65) | 85 (95–91) | 48 (46–51) | 84 (63–94) | 43 (39–47) | 85 (67–93) | ||
2009–2011 | I–II | 76 (75–77) | 93 (92–94) | 80 (78–82) | 93 (91–95) | 89 (87–91) | 94 (92–96) | 82 (78–85) | 96 (92–98) | 76 (70–82) | 97 (91–99) | |
III–IV | 45 (44–46) | 81 (78–84) | 45 (43–46) | 85 (74–92) | 63 (60–65) | 93 (85–96) | 47 (44–49) | 86 (66–94) | 44 (40–48) | 76 (61–86) | ||
Percent unit change,b P | I–-II | + 4, < 0.001 | + 2, < 0.001 | + 6, 0.001 | + 1, 0.546 | + 3, 0.118 | + 1, 0.508 | + 6, 0.035 | − 1, 0.562 | + < 1, 0.909 | + 10, 0.005 | |
III–IV | + 3, < 0.001 | + 7, 0.017 | + 3, 0.001 | + 1, 0.831 | −3, 0.087 | – < 1, 0.972 | + 3, 0.225 | −1, 0.890 | + 8, 0.007 | + 18, 0.085 | ||
12 months | 2003–2005 | I–II | 38 (36–39) | 64 (62–66) | 33 (30–36) | 64 (59–68) | 52 (48–57) | 62 (56–67) | 34 (29–39) | 66 (57–74) | 38 (30–45) | 51 (41–60) |
III–IV | 11 (11–12) | 34 (29–39) | 8 (7–9) | 49 (33–63) | 19 (17–22) | 45 (31–57) | 8 (6–10) | 37 (20–53) | 5 (3–8) | 13 (3–29) | ||
2006–2008 | I–II | 40 (39–41) | 65 (64–67) | 36 (33–38) | 64 (60–68) | 56 (53–60) | 69 (65–73) | 33 (29–38) | 71 (60–79) | 51 (43–59) | 67 (57–76) | |
III–IV | 12 (12–13) | 35 (31–39) | 8 (7–9) | 53 (38–64) | 19 (17–21) | 47 (36–57) | 11 (10–13) | 56 (35–73) | 12 (10–15) | 39 (23–55) | ||
2009–2011 | I–II | 44 (43–45) | 70 (68–71) | 45 (43–48) | 69 (65–72) | 55 (52–57) | 68 (65–71) | 44 (39–49) | 77 (70–83) | 42 (35–48) | 60 (50–68) | |
III–IV | 14 (14–15) | 47 (42–51) | 9 (8–10) | 41 (29–52) | 20 (18–22) | 53 (42–62) | 10 (8–11) | 46 (28–63) | 11 (9–14) | 17 (8–30) | ||
Percent unit change,b P | I–II | + 6, < 0.001 | + 5, < 0.001 | + 12, < 0.001 | + 5, 0.066 | + 3, 0.297 | + 6, 0.057 | + 10, 0.003 | + 11, 0.025 | + 4, 0.577 | + 9, 0.101 | |
III–IV | + 3, < 0.001 | + 13, < 0.001 | + 1, 0.001 | −8, 0.496 | + 1, 0.476 | + 8, 0.548 | + 2, 0.027 | + 10, 0.689 | + 6, < 0.001 | + 5, 0.238 | ||
Survival | Period | Stage | USA | The Netherlands | Belgium | Norway | Slovenia | |||||
Overall | Resected | Overall | Resected | Overall | Resected | Overall | Resected | Overall | Resected | |||
OS (95% CI)1 | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | OS (95% CI) | |||
36 months | 2003–2005 | I–II | 13 (13–14) | 27 (25–29) | 8 (7–10) | 18 (14–22) | 17 (14–21) | 24 (19–29) | 12 (9–16) | 28 (20–36) | 9 (6–14) | 11 (6–17) |
III–IV | 2 (2–2) | 7 (5–10) | 1 (1–2) | 14 (6–26) | 2 (2–4) | 8 (2–16) | 1 (1–2) | 10 (3–24) | 1 (< 1–2) | NA | ||
2006–2008 | I–II | 14 (14–15) | 29 (27–30) | 12 (10–13) | 24 (20–28) | 21 (18–23) | 28 (25–32) | 10 (7–14) | 32 (22–41) | 19 (14–26) | 27 (19–37) | |
III–IV | 2 (2–2) | 9 (7–11) | 1 (1–1) | 11 (5–21) | 2 (2–3) | 7 (3–14) | 2 (1–2) | 24 (10–42) | 2 (1–3) | 12 (4–26) | ||
2009–2011 | I–II | 17 (16–18) | 33 (31–34) | 16 (15–18) | 29 (26–32) | 20 (18–22) | 30 (26–33) | 15 (12–18) | 30 (23–37) | 12 (8–16) | 17 (11–24) | |
III–IV | 2 (2–2) | 11 (9–14) | 1 (1–1) | 12 (6–21) | 2 (1–3) | 10 (5–16) | 1 (1–2) | 14 (5–30) | 1 (< 1–1) | NA | ||
Percent unit change,b P | I–II | +4, < 0.001 | + 5, < 0.001 | + 8, < 0.001 | + 11, < 0.001 | + 3, 0.076 | + 5, 0.035 | + 2, 0.025 | + 2, 0.205 | + 2, 0.468 | + 6, 0.069 | |
III–IV | + < 1, < 0.001 | + 5, < 0.001 | + < 1, 0.005 | −2, 0.886 | −1, 0.285 | + 2, 0.317 | – < 1, 0.062 | +4, 0.785 | + < 1, 0.002 | NA, NA | ||
60 months | 2003–2005 | I–II | 9 (8–10) | 18 (17–20) | 4 (3–5) | 10 (7–13) | 11 (8–14) | 16 (12–21) | 9 (6–12) | 18 (12–25) | 7 (3–11) | 9 (5–15) |
III–IV | 1 (1–1) | 4 (2–6) | 1 (< 1–1) | 9 (3–20) | 1 (< 1–2) | 4 (1–11) | 1 (< 1–1) | 3 (< 1–15) | < 1 (< 1–1) | NA | ||
2006–2008 | I–II | 10 (9–11) | 20 (19–21) | 7 (6–9) | 15 (12–19) | 13 (11–15) | 18 (15–21) | 7 (4–9) | 20 (12–28) | 9 (5–14) | 13 (7–21) | |
III–IV | 1 (1–1) | 6 (5–9) | < 1 (< 1–1) | 6 (2–14) | 1 (1–2) | 5 (2–11) | 1 (< 1–1) | 4 (< 1–17) | 2 (1–3) | 12 (4–26) | ||
2009–2011 | I–II | NA | NA | 10 (8–12) | 18 (15–21) | 12 (10–14) | 18 (15–21) | 10 (7–13) | 20 (14–27) | 8 (5–12) | 11 (6–17) | |
III–IV | NA | NA | 1 (< 1–1) | 12 (6–21) | 1 (< 1–1) | 2 (< 1–7) | < 1 (< 1–1) | NA | < 1 (< 1–1) | NA | ||
Percent unit change,b P | I–II | NA, NA | NA, NA | + 6, < 0.001 | + 8, < 0.001 | + 1, 0.109 | + 2, 0.090 | + 1, 0.043 | + 2, 0.262 | + 2, 0.469 | + 2, 0.113 | |
III–IV | NA, NA | NA, NA | + < 1, 0.004 | + 3, 0.935 | –< 1, 0.290 | −2, 0.409 | - < 1, 0.069 | NA, NA | + < 1, 0.002 | NA, NA |