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Fig. 2 | BMC Medicine

Fig. 2

From: Quantifying where human acquisition of antibiotic resistance occurs: a mathematical modelling study

Fig. 2

The proportion of the total population with resistance that was acquired in the hospital at different parameter values. Here, red shading indicates that the minority in the total population acquired resistance in the hospital setting under bivariate (a–d) and multivariate parameter analysis (e). The dashed lines indicate the boundary of 50% resistance acquired in the hospital. Blue/green shaded areas indicate parameter combinations where the majority of human acquisition was in the hospital setting. The bivariate parameter combinations were of a varying transmission rates, b varying antibiotic exposure rates, c varying entry and exit rates into the hospital and d varying clearance and acquisition rates. Note that for a–d all other parameters are held at their case study values. e Most people with ARB in the total population had acquired ARB in the community setting for the majority of our LHS parameter samples. The targets (a–d) and cross (e) indicate the parameter combinations in our case study

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