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Table 3 Risk-benefit ratios for rotavirus vaccination

From: Updated cost-effectiveness and risk-benefit analysis of two infant rotavirus vaccination strategies in a high-income, low-endemic setting

 

Induced IS: prevented fatal cases

Induced IS: prevented hospitalized cases

Induced complicated IS: prevented fatal cases

Induced complicated IS: prevented hospitalized cases

All children

 Targeted vaccination

1:21 (1:12–1:33)

1:1707 (1:1494–1:1920)

1:445 (1:244–1:691)

1:35,564 (1:31,126–1:39,995)

 Universal vaccination

1:1.8 (1:1.0–1:2.8)

1:685 (1:603–1:767)

1:37 (1:20–1:59)

1:14,267 (1:12,566–1:15,974)

Targeted group

 Targeted vaccination

1:21 (1:12–1:33)

1:1707 (1:1494–1:1920)

1:445 (1:244–1:691)

1:35,564 (1:31,126–1:39,995)

 Universal vaccination

1:22 (1:12–1:34)

1:2012 (1:1773–1:2252)

1:455 (1:250–1:706)

1:41,913 (1:36,942–1:46,921)

Healthy children

 Targeted vaccination

NA

NA

NA

NA

 Universal vaccination

1:0.05 (1:0.00–1:0.16)

1:571 (1:503–1:639)

1:1.0 (1:0.03–1:3.24)

1:11,896 (1:10,475–1:13,319)