Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study

Table 4 Association of each factor with incident active TB

	Univariable analysis HR (95% CI)	Multivariable analysis HR (95% CI)
Factor 1 (High carotenoids and low IL-18)	0.56 (0.38–0.82)	0.48 (0.26–0.87)
Factor 2 (Other nutrients)	0.65 (0.45–0.95)	0.98 (0.48–2.05)
Factor 3 (Inflammation)	1.15 (0.83–1.54)	0.91 (0.57–1.45)

The association of each factor with incident active TB was determined in univariable and multivariable Cox regression models. Baseline variables including sex, age, country, treatment arm, body mass index (BMI), CD4 count, viral load, baseline TB status, anemia, and hypoalbuminemia were adjusted for in the multivariable models. N = 220 (47 cases, 173 controls)

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