Fig. 5
In vitro artesunate sensitivities at different levels of in vivo resistance. In vitro artesunate (AS) dose–response curves, with SD error bars, are shown for parasites resistant in vivo to (a) single dose AS 30 mg/kg (purple), 120 mg/kg (blue), and 240 mg/kg (red) or (b) 2-day regimen AS 19.2 mg/kg/dose (green) and 80 mg/kg/dose (orange), and compared to the artemisinin-sensitive progenitor strain (black). Mean IC50 values (nM) are indicated in parentheses