Fig. 1

Schematic of the meta-population model structure that focuses on the northern part of South America and the Caribbean islands. Each city consists of individuals who are assumed to be susceptible (S), pre-infectious (E), infectious (I) or recovered (R) from ZIKV infection. Movement of pre-infectious individuals between cities is modelled assuming different population flows, where a gravity model is illustrated. Movements to cities outside of the plotted area are not illustrated