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Fig. 3 | BMC Medicine

Fig. 3

From: Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

Fig. 3

Volcano plot of 45 exosomal miRNAs. Volcano plots of p values vs fold changes compare the expression of exosomal miRNAs in 435 BC (a), 211 HER2-positive (b), and 224 TNBC patients (c) with that of 20 healthy women, as well as between HER2-positive and TNBC patients (d). The grey dashed line refers to the threshold value corresponding to a corrected p value of p = 0.05. Significantly downregulated exosomal miRNAs are shown as green dots, significantly upregulated exosomal miRNAs as red dots. Grey dots represent non-significant changes. p values are calculated by the Student t test and corrected according to the Benjamini and Hochberg method

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