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Table 1 Characteristics of included studies

From: Registration of published randomized trials: a systematic review and meta-analysis

Reference

Medical specialty

Time period for RCT publication

Identification of trials

Journals (N)

Trials (N)

Assessment of registration

Registries searched

Reporting

Search

Email

CT.gov

ISRCTN

WHO ICTRP

ANZCTR

National registries

Ostervig [59]

Anesthesiology

2009–2014

Single journal

1

200

Yes

Yes

No

Yes

Yes

No

No

Yes

Jones [49]

Anesthesiology

2007; 2010; 2013; 2010

Selection of high IF journals

6

860

Yes

Yes

Yes

Yes

Yes

Yes

No

No

Nankervis [56]

Atopic dermatitis

01/2007–07/2011

SR of eczema RCTs

109

Yes

Yes

No

No

No

Yes

No

No

Mathieu [22]

Cardiology, rheumatology, gastroenterology

2008

SR of RCTs in cardiology, rheumatology, and gastroenterology

22

323

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Wiebe [71]

Cardio-thoracic surgery

2008–2015

Selection of high IF journals

4

287

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Emdin [42, 58]

Cardiovascular disease

12/2012

SR of cardiovascular disease RCTs

191

Yes

Yes

No

No

No

Yes

No

No

Cybulski [37]

Clinical psychology

2013

Selection of high IF journals

25

101

Yes

Yes

Yes

Yes

No

Yes

No

No

Anand [32]

Critical care

01/2005–08/2011

SR of RCTs in critical care

90

Yes

Yes

Yes

Yes

No

No

Yes

No

Shinohara [66]

Depression

2011–2013

SR of RCTs of cognitive behavioral therapy and new-generation antidepressants

170

Yes

No

Yes

Unclear

Jones [48]

Emergency medicine

2008–2011

Selection of high IF journals

5

123

Yes

Yes

No

Yes

Yes

Yes

No

No

Farquhar [43, 44]

Fertility medicine

2010–2014

SR of RCTs of fertility treatments

NA

693

Yes

Yes

Yes

Yes

No

Yes

No

No

Li [52]

Gastroenterology and hepatology

2009–2012

Selection of high IF journals

10

305

Yes

Yes

No

Yes

Yes

Yes

Yes

No

Mann [53]

Geriatrics

2008–2012

Selection of high IF journals

5

220

Yes

Yes

No

No

No

Yes

No

No

McGee [54]

Kidney transplantation

10/2005–12/2010

SR of kidney transplantation RCTs

307

No

Yes

No

No

No

Yes

No

No

Gray [46]

Nursing

11/2011–09/2016

Key general and mental health journals in nursing

3

135

Yes

Yes

Yes

Yes

Yes

No

No

Yes

Byrne [36]

Obesity

01/2011–06/2016

Selection of specialty journals

4

223

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

You [33, 72]

Oncology

2005–2009

Journals thought to publish majority of oncology RCTs

10

366

Yes

Yes

No

Yes

Yes

No

No

No

Smail-Faugeron [68]

Oral health

2013

Selection of high IF journals

15

317

Yes

Yes

No

No

No

Yes

No

No

Hamm [21]

Pediatrics

2007

SR of pediatric RCTs

300

Yes

Yes

No

Yes

Yes

Yes

No

Yes

Gates [45]

Pediatrics

2012

SR of pediatric RCTs

300

Yes

Yes

No

Yes

Yes

No

No

No

Rosati [64]

Pediatrics

07/2013–11/2013

Single journal

1

20

Yes

Yes

No

Yes

Yes

No

Yes

Yes

Pinto [61]

Physical therapy

2009

Indexed in PEDro

200

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Pidgeon [60]

Plastic surgery

04/2014–03/2015

Selection of high IF journals

3

24

No

Yes

No

Yes

Yes

Yes

No

No

Scott [65]

Psychiatry

2009–2013

Selection of high IF journals

5

181

Yes

Yes

Yes

Yes

Yes

No

No

Yes

Milette [55]

Psychosomatic and behavioral medicine

01/2008–09/2009

Selection of high IF journals

4

63

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Riehm [63]

Psychosomatic and behavioral medicine

01/2013–10/2014

Selection of high IF journals

4

76

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Bradley [35]

Psychotherapy

2010–2014

Selection of high IF journals

5

112

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Sims [67]

Shoulder arthroplasty

2005–2015

SR of shoulder arthroplasty RCTs

10

37

Yes

Yes

Yes

Yes

Yes

Yes

No

No

Killeen [50]

Surgery

2009–2010

Selection of high IF journals

10

246

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Hardt [47]

Surgery

06/2012–12/2012

Selection of high IF journals

10

103

Yes

Yes

No

No

No

Yes

No

No

Kunath [51]

Urology

2009

Selection of high IF journals

10

106

Yes

Yes

No

No

No

Yes

No

No

Potentially overlapping studies

Bonnot [34]

Anesthesiology

2013

Selection of high IF journals

12

183

Yes

Yes

Yes

No

No

Yes

No

No

El-Boghdadly [41]

Anesthesiology

01/201412/2016

Single journal

1

90

Yes

Yes

No

Yes

Yes

No

Yes

Yes

Norris [57]

Diabetes, osteoporosis, lip-modifying agents

2005–2010

Comparative effectiveness reviews

299

No

Yes

No

No

No

Yes

No

No

Dekkers [40]

Multiple

2004–2012

Trial protocols submitted to ethics committee

54

Yes

Yes

No

No

No

Yes

No

No

Dechartres [38]

Multiple

2006–2014

Cochrane reviews

322

Yes

Yes

Yes

Yes

No

Yes

No

No

Dekkers [39]

Multiple

02/2009

SR of non-inferiority RCTs in Core Clinical Journals

121

133

Yes

Yes

No

Yes

Yes

No

No

No

Reveiz [62]

Multiple

2010

SR of RCTs from Latin America and Caribbean

526

No

Yes

No

No

No

Yes

No

No

Van de Wetering [70]

Multiple

11/2010

Core Clinical Journals

121

302

Yes

Yes

Yes

Yes

Yes

Yes

No

No

Walker [69]

Multiple

05/2011–05/2012

Selection of high IF journals

2

76

Yes

Yes

No

Yes

Yes

No

No

Yes

  1. SR systematic review, RCT randomized controlled trial, IF impact factor, PEDro Physiotherapy Evidence Database, CT.gov ClinicalTrials.gov, ISCRCTN International Standard Randomised Controlled Trials Number, WHO ICTRP World Health Organization International Clinical Trials Registry Platform, ANZCTR Australian New Zealand Clinical Trials Registry