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Table 2 Treatment and covariate effects on unfavourable outcome for men (N = 974)

From: Gender differences in tuberculosis treatment outcomes: a post hoc analysis of the REMoxTB study

  r/n OR (unadjusted), 95% CI p aOR (adjusted), 95% CI p
Treatment
 HRZE 30/326 (33)    1.0  
 2MHRZ/2MHR 55/312 (32) 2.22 (1.36–3.62) 0.001 2.24 (1.37–3.65) 0.001
 2EMRZ/2MR 78/336 (35) 3.31 (2.07–5.29) < 0.001 3.31 (2.07–5.28) < 0.001
Age
 ≤ 30 years 58/435 1.0   1.0  
 > 30 years 105/539 1.46 (1.00–2.12) 0.045 1.48 (1.02–2.14) 0.037
BMI
 < 18.5 105/547 1.0   1.0  
 ≥ 18.5 58/427 0.65 (0.45–0.93) 0.020 0.64 (0.44–0.92) 0.017
Race
 Asian 50/311 1.0    
 Black 70/430 0.85 (0.55–1.32) 0.469
 Mixed race and Caucasian 43/233 0.97 (0.58–1.61) 0.902   
Smoking
 Never smoked 39/334 1.0   1.0  
 Ever smoked 124/640 1.61 (1.04–2.49) 0.034 1.60 (1.07–2.40) 0.023
HIV
 Negative 143/922 (95) 1.0   1.0  
 Positive 20/52 4.26 (2.22–8.18) < 0.001 3.97 (2.12–7.42) < 0.001
Cavities
 No cavities 16/198 1.0   1.0  
 Cavities 147/776 2.78 (1.59–4.85) < 0.001 2.78 (1.59–4.84) < 0.001
  1. r number with unfavourable outcome
  2. n total in category