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Fig. 4 | BMC Medicine

Fig. 4

From: Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children

Fig. 4

Association between CSP Ig responses after vaccination and RTS,S-induced protection. a Ratio of cytophilic IgG1 and IgG3 vs non-cytophilic IgG2 and IgG4 antibodies, and increment of IgG levels between month 0 and month 3 in protected (NM = no clinical malaria) and non-protected (M = clinical malaria). b Difference between month 3 and month 0 (M3–M0) cytophilic/non-cytophilic ratios. Groups were compared through t tests and p values adjusted by Holm

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