|
Cytokines**
|
Unstimulated
|
TLR3 responses
|
TLR7/8 responses
|
TLR9 responses
|
|---|
|
Crude
|
Crude
|
Ratios
|
Crude
|
Ratios
|
Crude
|
Ratios
|
|---|
|
AHR (95% CI)
|
AHR (95% CI)
|
AHR (95% CI)
|
AHR (95% CI)
|
AHR (95% CI)
|
AHR (95% CI)
|
AHR (95% CI)
|
|---|
|
Pro
|
IFN-α
| | |
0.24 (0.05–1.10)
| | | | |
|
IL-1RA*
| | | |
0.61 (0.36–1.03)
|
0.70 (0.50–0.98)
| | |
|
IL-1β
|
1.16 (0.98–1.37)
|
1.15 (0.97–1.36)
| | | |
1.18 (1.01–1.39)
| |
|
TNF
| | | | | | | |
|
Anti
|
IL-10
| |
1.12 (0.99–1.25)
| | | | | |
|
IL-7
| |
1.80 (1.26–2.58)
|
1.54 (1.11–2.15)
| | | | |
|
Th1
|
IL-15
| | | | | |
1.22 (0.96–1.54)
| |
|
IL-12*
|
1.28 (0.97–1.69)
|
1.26 (0.95–1.68)
|
0.27 (0.07–1.15)
| |
0.76 (0.59–0.98)
| |
0.46 (0.20–1.04)
|
|
IL-2
| | | | | | | |
|
IL-2R
| | | | | | | |
|
IFN-γ
| | | | | | | |
|
Th2
|
IL-13
| | | | | | | |
|
IL-5
| | | | | | | |
|
IL-4
| | | | | | | |
|
Th17
|
IL-17
| | | | | | | |
|
IL-6
| | | | | | | |
|
Chemokines
|
IL-8
| | | | | | | |
|
IP-10*
|
0.64 (0.38–1.08)
|
0.66 (0.46–0.93)
| | | |
0.75 (0.59–0.96)
| |
|
MCP-1
| | | | | | | |
|
MIG
| | | | | | |
0.77 (0.56–1.05)
|
|
MIP-1α
| | | | | |
1.13 (0.97–1.31)
| |
|
MIP-1β
| | | | | | | |
|
RANTES
| | | | | | | |
|
EOTAXIN
|
1.83 (1.11–3.01)
|
1.60 (0.99–2.58)
|
0.19 (0.03–1.14)
|
1.72 (1.01–2.94)
| | |
0.46 (0.24–0.86)
|
|
Growth factors
|
EGF
| | | |
0.29 (0.08–1.07)
| | | |
|
FGF
| |
1.63 (0.91–2.93)
| | | | | |
|
G-CSF
|
1.24 (0.97–1.57)
| | | | | | |
|
GM-CSF*
| | | |
1.28 (1.01–1.15)
| | | |
|
HGF
| | | | | | | |
|
VEGF
| | | | | | | |
- HR hazard ratio, CI confidence interval, Pro proinflammatory cytokines, Anti anti-inflammatory cytokines, Th1 Th1-type cytokines, Th2 Th2-type cytokines, Th17 Th17-type cytokines. **Only results of cox proportional analysis for cytokines with P value (P) ≤ 0.100 are presented. *Cytokines whose levels were significantly modified by prenatal malaria exposure categories. Significant results are shwon in italic
