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Table 7 Sensitivity analysis of complete case analysis compared to imputed ADL adjusted model with respect to care home admission at discharge (n = 236)

From: Living at home after emergency hospital admission: prospective cohort study in older adults with and without cognitive spectrum disorder

Variables

N (%; 95%CI) with new care home admission at discharge

Adjusted model

Sensitivity analysis*

Complete case analysis

Total N = 236

Odds ratio (95% confidence interval)

Age

65–74 (n = 1777)

12 (0.7; 0.4–1.2)

1

1

75–84 (n = 2318)

84 (3.6; 2.9–4.5)

3.79 (2.04–7.07)

3.17 (1.69–5.96)

≥ 85 (n = 1475)

140 (9.5; 8.1–11.1)

6.43 (3.47–11.89)

4.54 (2.44–8.44)

Sex

Women (n = 3138)

167 (5.3; 4.6–6.2)

1

1

Men (n = 2432)

69 (2.8; 2.3–3.6)

0.68 (0.50–0.93)

0.73 (0.53–1.00)

Deprivation (SIMD quintile)

1 most deprived (n = 1151)

26 (2.3; 1.6–3.3)

0.52 (0.30–0.90)

0.50 (0.28–0.86)

2 (n = 1473)

56 (3.8; 2.9–4.9)

0.88 (0.56–1.39)

0.86 (0.54–1.38)

3 (n = 1266)

62 (4.9; 3.8–6.2)

1.02 (0.65–1.61)

0.95 (0.60–1.52)

4 (n = 853)

55 (6.4; 5.0–8.3)

1.26 (0.79–2.01)

1.17 (0.72–1.89)

5 most affluent (n = 827)

37 (4.5; 3.3–6.1)

1

1

Charlson Comorbidity Index (CCI)

CCI 0 (n = 1424)

83 (5.8; 4.7–7.2)

1

1

CCI 1 (n = 1496)

58 (3.9; 3.0–5.0)

1.00 (0.68–1.46)

0.97 (0.66–1.45)

CCI 2 to 5 (n = 2233)

83 (3.7; 3.0–4.6)

0.87 (0.61–1.23)

0.89 (0.62–1.28)

CCI ≥ 6 (n = 417)

12 (2.9; 1.7–5.0)

0.98 (0.50–1.90)

0.96 (0.48–1.92)

Cognitive spectrum disorder

None (n = 3903)

55 (1.4; 1.1–1.8)

1

1

Delirium alone (n = 821)

52 (6.3; 4.9–8.2)

3.04 (2.03–4.57)

2.93 (1.91–4.49)

Known dementia (n = 335)

36 (10.7; 7.9–14.5)

4.28 (2.69–6.82)

4.09 (2.51–6.67)

Delirium superimposed on dementia (n = 285)

75 (26.3; 21.6–31.7)

11.72 (7.82–17.56)

9.14 (5.98–13.99)

Unspecified cognitive impairment (n = 226)

18 (8.0; 5.1–12.2)

3.65 (2.06–6.47)

2.98 (1.66–5.35)

No. of medications

0–5 (n = 1746)

99 (5.7; 4.7–6.9)

1

1

6–10 (n = 2204)

97 (4.4; 3.6–5.3)

0.74 (0.53–1.02)

0.70 (0.51–0.98)

> 10 (n = 1620)

40 (2.5; 1.8–3.4)

0.42 (0.28–0.64)

0.35 (0.23–0.54)

Activities of daily living (ADL) score

Persistently high ADL (n = 1956)

31 (1.6; 1.1–2.2)

1

1

Changed ADL (n = 1341)

92 (6.9; 5.6–8.3)

2.99 (2.06–4.36)

4.12 (2.61–6.49)

Persistently low ADL (n = 681)

102 (15.0; 12.5–17.9)

1.89 (1.31–2.71)

2.51 (1.62–3.89)

  1. Italic text denotes results which are statistically significant
  2. 95%CI 95% confidence interval; SIMD Scottish Index of Multiple Deprivation
  3. *Complete case analysis based on data from n = 3978 (71.4%) who had complete data record