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Table 3 Predictors of virologic failure (HBV viral load ≥ 69 IU/mL) after 12 months of antiviral treatment, Addis Ababa, Ethiopia

From: Treatment of chronic hepatitis B in sub-Saharan Africa: 1-year results of a pilot program in Ethiopia

Baseline variable

Total (n = 189)

Virologic failure (n = 28)

Crude

Adjusted

n (%)

n (%)

OR (95% CI)

p

OR (95% CI)

p

Sex

 Women

44 (23.3)

5 (17.9)

1

   

 Men

145 (76.7)

23 (82.1)

1.52 (0.54–4.26)

0.426

  

Age, years (per 1-year increment)

35 (26–41)a

35 (26–41) a

1.00 (0.96–1.04)

0.952

  

Decompensated liver disease

 No

126 (66.7)

20 (71.4)

1

   

 Yes

63 (33.3)

8 (28.6)

0.77 (0.32–1.86)

0.563

  

HBV viral load, IU/mLb

 ≤ 106

116 (62.0)

12 (42.9)

1

 

1

 

 > 106

71 (38.0)

16 (57.1)

2.52 (1.11–5.71)

0.026

2.41 (1.04–5.55)

0.039

Adherencec

 ≥ 95%

160 (85.1)

19 (67.9)

1

 

1

 

 < 95%

28 (14.9)

9 (32.1)

3.74 (1.47–9.49)

0.006

3.43 (1.33–8.88)

0.011

  1. HBV hepatitis B virus, OR odds ratio, CI confidence interval
  2. aMedian (interquartile range)
  3. bTwo missing values
  4. cOne missing value