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Table 3 Predictors of virologic failure (HBV viral load ≥ 69 IU/mL) after 12 months of antiviral treatment, Addis Ababa, Ethiopia

From: Treatment of chronic hepatitis B in sub-Saharan Africa: 1-year results of a pilot program in Ethiopia

Baseline variable Total (n = 189) Virologic failure (n = 28) Crude Adjusted
n (%) n (%) OR (95% CI) p OR (95% CI) p
Sex
 Women 44 (23.3) 5 (17.9) 1    
 Men 145 (76.7) 23 (82.1) 1.52 (0.54–4.26) 0.426   
Age, years (per 1-year increment) 35 (26–41)a 35 (26–41) a 1.00 (0.96–1.04) 0.952   
Decompensated liver disease
 No 126 (66.7) 20 (71.4) 1    
 Yes 63 (33.3) 8 (28.6) 0.77 (0.32–1.86) 0.563   
HBV viral load, IU/mLb
 ≤ 106 116 (62.0) 12 (42.9) 1   1  
 > 106 71 (38.0) 16 (57.1) 2.52 (1.11–5.71) 0.026 2.41 (1.04–5.55) 0.039
Adherencec
 ≥ 95% 160 (85.1) 19 (67.9) 1   1  
 < 95% 28 (14.9) 9 (32.1) 3.74 (1.47–9.49) 0.006 3.43 (1.33–8.88) 0.011
  1. HBV hepatitis B virus, OR odds ratio, CI confidence interval
  2. aMedian (interquartile range)
  3. bTwo missing values
  4. cOne missing value