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Table 1 Study characteristics of articles included in the meta-analysis and/or qualitative synthesis

From: The impact of repeated vaccination on influenza vaccine effectiveness: a systematic review and meta-analysis

Author, publication year

Country

Study design

Current season

Prior season

Influenza type

Age group

Jimenez-Jorge et al., 2012 [19]

Spain

Test-negative case-control

2010–2011

2009–2010

H1N1

All ages

Martinez-Baz et al., 2013 [20]

Spain

Test-negative case-control

2010–2011

2009–2010

H1N1

All ages

Skowronski et al., 2012 [28]

Canada

Test-negative case-control

2010–2011

2009–2010

H1N1

All ages

Syrjanen et al., 2014 [33]

Finland

Cohort

2010–2011

2009–2010

H1N1

18–75 years

Fu et al., 2015 [17]

China

Case-control

2012–2013

2011–2012

H1N1

(a) 20–35 months, 1 current dose; (b) 20–35 months, 2 current doses; (c) 3–6 years

Gaglani et al., 2016 [18]

USA

Test-negative case-control

2013–2014

2009–2010 to 2012–2013

H1N1

≥ 9 years

Ohmit et al., 2016 [22]

USA

Prospective cohort study

2013–2014

2012–2013

H1N1

(a) 9 and older; (b) under 9 years

Thompson et al., 2014b [35]

USA

Case-control

2010–2011 and 2011–2012

2009–2010 and 2010–2011

H1N1, H3N2, B

Mean age 30 years

Skowronski et al., 2014b [29]

Canada

Test-negative case-control

2011–2012

2010–2011

H1N1, H3N2, B

≥ 2 years

Rondy et al., 2015 [25]

France, Italy, Lithuania, Spain

Test-negative case-control

2012–2013

2011–2012

H1N1, H3N2, B

≥ 18 years

Skowronski et al., 2014a [27]

Canada

Test-negative case-control

2012–2013

2011–2012

H1N1, H3N2, B

≥ 2 years

Valenciano et al., 2016 [36]

Germany, Hungary, Ireland, Italy, Poland, Portugal, Romania, Spain

Test-negative case-control

2014–2015

2013–2014

H1N1, H3N2, B

All ages

Pebody et al., 2013 [24]

UK

Test-negative case-control

2010–2011

2009–2010

H1N1, B

All ages

Skowronski et al., 2015 [30]

Canada

Test-negative case-control

2013–2014

2012–2013

H1N1, B

≥ 2 years

McLean et al., 2014 [6]

USA

Test-negative case-control

2004–2005 to 2012–2013

Variable

H3N2, B

(a) 9 to 49; (b) 50 and older

McLean et al., 2015 [21]

USA

Test-negative case-control

2012–2013

2011–2012

H3N2, B

(a) 9 to 17; (b) 18 to 49; (c) 50 to 64; (d) 65 and older

Thompson et al., 2016 [34]

USA

Test-negative case-control

2011–2012 and 2012–2013

2010–2011 and 2011–2012

H3N2, B

2–8 years, 1 dose prior season

Skowronski et al., 2016 [7]

Canada

Test-negative case-control

2014–2015

2013–2014

H3N2, B

≥ 2 years

Simpson et al., 2015a[26]

Scotland

Test-negative case-control

2008–2009

9 prior seasons

All influenza

All ages

Castilla et al., 2011a [15]

Spain

Nested test-negative case- control

2010–2011

2009–2010

All influenza

All ages

Ohmit et al., 2014 [8]

USA

Test-negative case-control

2011–2012

2010–2011

H3N2

≥ 9 years

Ohmit et al., 2015a [23]

USA

Prospective cohort study

2012–2013

2011–2012

All influenza

All ages

Smithgall et al., 2016a [31]

USA

Surveillance

2013–2014

2012–2013

All influenza

All ages

Castilla et al., 2016a [16]

Spain

Test-negative case-control

2014–2015

2013–2014 and 2012–2013

All influenza

All ages

Sullivan and Kelly, 2013a [32]

Australia

Re-analysis

(a) Southern Hemisphere 2011; (b) Southern Hemisphere 2012

Southern Hemisphere 2010 and 2011

All influenza

All ages

Petrie et al., 2016 [37]

USA

Test-negative case-control

2014–2015

2013–2014

H3N2

≥ 18 years

  1. aStudy not included in meta-analysis
  2. bStudy population included pregnant women only