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Table 1 Demographic and clinical characteristics

From: NMR-based metabolomics identifies patients at high risk of death within two years after acute myocardial infarction in the AMI-Florence II cohort

  Survived (n=832) Died (n=146) p-value
Demographic characteristics,
 Age (years), median (IQR) 72 (62–80) 82 (78–83) < 2.20×10−16
 Female sex, n (%) 278 (33.4) 67 (45.9) 4.86×10−03
Cardiovascular risk factors, n (%)
 Hypertension 537 (64.5) 104 (71.2) 1.21×10−01
 Dyslipidemia 294 (35.3) 32 (21.9) 3.55×10−03
 Current smokers 226 (27.2) 20 (13.7) 1.45×10−04
 Ex-smokers 21 (2.5) 8 (5.5) 4.01×10−01
 CAD 220 (26.4) 17 (11.6) 5.03×10−04
 Diabetes 197 (23.7) 61 (41.8) 6.32×10−06
Medical history, n (%)
 Myocardial infarction 164 (19.7) 48 (32.9) 5.23×10−04
 Angina, onset > 1 month 119 (14.3) 24 (16.4) 8.96×10−01
 Angina, onset ≤ 1 month 149 (17.9) 15 (10.3) 3.78×10−02
 CABG 41 (4.9) 10 (6.8) 4.39×10−01
 PCI 136 (16.3) 32 (21.9) 1.20×10−01
 Chronic heart failure 33 (4.0) 26 (17.8) 2.62×10−10
 Atrial fibrillation 42 (5.0) 21 (14.4) 4.60×10−05
 Cerebrovascular disease 50 (6.0) 28 (19.2) 1.28×10−07
Presentation features
 ACS classification, STEMI, n (%) 343 (41.2) 35 (24.0) 1.15×10−04
 Killip II–IV, n (%) 114 (13.7) 61 (41.8) 6.33×10−16
 Creatinine > 1.2 mg/dL, n (%) 129 (15.5) 54 (37.0) 4.08×10−09
 Heart rate (bpm), median (IQR) 80 (67–91) 90 (80–105) 3.66×10−06
 Positive peak troponine maximum, n (%) 804 (96.6) 143 (97.9) 6.98×10−01
 Positive peak CK-MB maximum, n (%) 422 (50.7) 50 (32.2) 1.88×10−03
 GRACE score > 118, n (%) 687 (82.6) 123 (84.2) 1.62×10−01
  1. CAD coronary artery diseases, CABG coronary artery bypass grafting, PCI percutaneous coronary intervention, ACS acute coronary syndrome, STEMI ST-segment elevation myocardial infarction, CK-MB creatine kinase-MB, GRACE Global Registry of Acute Coronary Events
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