Table 1 Summary of characteristics of included studies

Disease or condition

AUD

38

Drug addiction or smoking ± AUD

18

Psychiatric disorders ± AUD

13

Impulse control disorders

9

Obesity or eating disorders

6

Inflammatory disorders

3

malignancies

2

Target dose of naltrexone^a (mg)

≤4.5

5

16–49

7

50

61

100

12

>100

8

Mean age where given^b (years)

10 to <20

2

20 to <30

2

30 to <40

11

40 to <50

62

50 to <60

3

≥60

2

Length of study^c (weeks)

4–7

5

8–11

17

12–15

42

16–25

18

26–52

6