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Table 2 Risk of bias of included studies

From: High-throughput, non-invasive prenatal testing for fetal rhesus D status in RhD-negative women: a systematic review and meta-analysis

Study Risk of bias Applicability concerns
Patient selection Index test Reference standard Flow and timing Patient selection Index test Reference standard
Akolekar (2011) [19] High High Unclear Unclear High Low Unclear
Banch-Clausen (2014) [6] Low Low Low Low Unclear Low Low
Chitty (2014) [16] Low Low Low Low Low Low Low
Finning (2008) [17] Low Low Low Low Low Low Low
Grande (2013) [25] Low Low Low Low Low Low Low
Soothill (2015) [18] Low Unclear Low Low Low Low Low
Thurik (2015) [7] Low High Low High Low Low Low
Wikman (2012) [20] Low Low Low Low Unclear High Low
  1. High: high risk of bias; Low: low risk of bias
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