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Table 1 Descriptive statistics of the study participants

From: Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure

 

Previously naïve

Previously exposed

Number of participants

20

41

Female sex (%)

3 (15.0)

7 (17.1)

Median age, years (range)

34 (21–59)

40 (27–70)

Median cumulative time of residency in an endemic area, years (range)

0 (0–3)

25 (13–39)

Median time since residency in an endemic area, years (range)

–

14 (0–46)

Median time from symptom onset to diagnosis, days (range)

3 (0–12)

3 (1–13)

Median parasitaemia, % infected RBCs (range)

0.9 (< 0.1–8.0)

0.3 (< 0.1–17)

Late treatment failure* (%)

5 (25)

0 (0)

Severe malaria† (%)

1 (5)

4 (9.7)

Treated in intensive care unit (%)

1 (5)

2 (4.9)

Initial intraveneous artesunate treatment (%)

6 (30)

10 (24.4)

  1. *Presented with recrudescent parasitaemia and fever 20–28 days following initial treatment
  2. †Severe malaria was defined according to the WHO classification