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Table 5 Projected costs and epidemiologic outcomes over 20 years

From: The potential impact and cost-effectiveness of tobacco reduction strategies for tuberculosis prevention in Canadian Inuit communities

Outcomes per 1000 persons Cost (95% UR) TB incidence (95% UR) TB deaths (95% UR) QALYs (95% UR)
 Status quo $816,588 ($589,629–$1,144,728) 18.88 (14.81–23.92) 1.83 (1.12–3.30) 14,963.00 (14,935.98–14,966.22)
 Increased taxation $800,890 ($579,868–$1,120,755) 18.43 (14.53–23.30) 1.76 (1.11–3.16) 14,963.66 (14,937.19–14,966.72)
 Pharmacotherapy and counselling $955,921 ($726,763–$1,279,070) 18.71 (14.71–23.68) 1.80 (1.12–3.25) 14,963.25 (14,936.45–14,966.41)
 Pharmacotherapy, counselling, and mass media $1,012,812 ($782,975–$1,333,469) 18.62 (14.65–23.56) 1.79 (1.11–3.22) 14,963.40 (14,936.71–14,966.52)
 All [taxation + mass media + pharmacotherapy + counselling] $981,366 ($764,325–$1,283,894) 17.72 (14.06–22.32) 1.64 (1.03–2.93) 14,964.76 (14,939.14–14,967.55)
Costs per person and ICERs—status quo as comparator Incr. cost vs status quo Incr. cost per TB case averted Incr. cost per TB death averted Incr. cost per QALY gained
 Status quo [comparator]
 Increased taxation Saves $16 ($8 - $26) Dominant Dominant Dominant
 Pharmacotherapy and counselling $142 ($125–$146) $837,464 ($527,624–$1,462,565) $4,990,117 ($2,495,571–$8,928,090) $542,594 ($259,691–$812,827)
 Pharmacotherapy, counselling, and mass media $200 ($175–$206) $760,387 ($478,141–$1,330,478) $4,530,453 ($2,264,728–$8,115,767) $492,482 ($235,705–$738,813)
 All [taxation + mass media + pharmacotherapy + counselling] $181 ($157–$196) $142,907 ($78,263–$271,386) $852,009 ($398,407–$1,594,941) $93,717 ($41,304–$147,677)
ICERs per person—increased taxation as a comparator Incr. cost vs Increased taxation Incr. cost per TB case averted Incr. cost per TB death averted Incr. cost per QALY gained
 Status quo $16 ($8–$26) Dominated Dominated Dominated
 Increased taxation [comparator]
 Pharmacotherapy and counselling $155 ($139–$164) Dominated Dominated Dominated
 Pharmacotherapy, counselling, and mass media $212 ($192–$222) Dominated Dominated Dominated
 All [taxation + mass media + pharmacotherapy + counselling] $180 ($154–$195) $256,022 ($151,962–$465,895) $1,522,952 ($740,992–$2,789,202) $164,369 ($76,252–$252,203)
  1. UR uncertainty range, ICER incremental cost-effectiveness ratio, Incr incremental
  2. Numbers in parentheses represent 95% UR i.e. uncertainty ranges