Table 5 Projected costs and epidemiologic outcomes over 20 years

Outcomes per 1000 persons

Cost (95% UR)

TB incidence (95% UR)

TB deaths (95% UR)

QALYs (95% UR)

 Status quo

$816,588 ($589,629–$1,144,728)

18.88 (14.81–23.92)

1.83 (1.12–3.30)

14,963.00 (14,935.98–14,966.22)

 Increased taxation

$800,890 ($579,868–$1,120,755)

18.43 (14.53–23.30)

1.76 (1.11–3.16)

14,963.66 (14,937.19–14,966.72)

 Pharmacotherapy and counselling

$955,921 ($726,763–$1,279,070)

18.71 (14.71–23.68)

1.80 (1.12–3.25)

14,963.25 (14,936.45–14,966.41)

 Pharmacotherapy, counselling, and mass media

$1,012,812 ($782,975–$1,333,469)

18.62 (14.65–23.56)

1.79 (1.11–3.22)

14,963.40 (14,936.71–14,966.52)

 All [taxation + mass media + pharmacotherapy + counselling]

$981,366 ($764,325–$1,283,894)

17.72 (14.06–22.32)

1.64 (1.03–2.93)

14,964.76 (14,939.14–14,967.55)

Costs per person and ICERs—status quo as comparator

Incr. cost vs status quo

Incr. cost per TB case averted

Incr. cost per TB death averted

Incr. cost per QALY gained

 Status quo [comparator]

–

–

–

–

 Increased taxation

Saves $16 ($8 - $26)

Dominant

Dominant

Dominant

 Pharmacotherapy and counselling

$142 ($125–$146)

$837,464 ($527,624–$1,462,565)

$4,990,117 ($2,495,571–$8,928,090)

$542,594 ($259,691–$812,827)

 Pharmacotherapy, counselling, and mass media

$200 ($175–$206)

$760,387 ($478,141–$1,330,478)

$4,530,453 ($2,264,728–$8,115,767)

$492,482 ($235,705–$738,813)

 All [taxation + mass media + pharmacotherapy + counselling]

$181 ($157–$196)

$142,907 ($78,263–$271,386)

$852,009 ($398,407–$1,594,941)

$93,717 ($41,304–$147,677)

ICERs per person—increased taxation as a comparator

Incr. cost vs Increased taxation

Incr. cost per TB case averted

Incr. cost per TB death averted

Incr. cost per QALY gained

 Status quo

$16 ($8–$26)

Dominated

Dominated

Dominated

 Increased taxation [comparator]

–

–

–

–

 Pharmacotherapy and counselling

$155 ($139–$164)

Dominated

Dominated

Dominated

 Pharmacotherapy, counselling, and mass media

$212 ($192–$222)

Dominated

Dominated

Dominated

 All [taxation + mass media + pharmacotherapy + counselling]

$180 ($154–$195)

$256,022 ($151,962–$465,895)

$1,522,952 ($740,992–$2,789,202)

$164,369 ($76,252–$252,203)