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Fig. 6 | BMC Medicine

Fig. 6

From: Cathelicidin-related antimicrobial peptide protects against myocardial ischemia/reperfusion injury

Fig. 6

Identification of potential regulators of CRAMP and their effect in cardiomyocyte apoptosis. a The protein levels of c-Jun, Rela, VDR, and C/EBPα were analyzed by Western blot in neonatal rat cardiomyocytes (NRCMs) treated with oxygen glucose deprivation/reperfusion (OGDR) (n = 3). b The protein levels of c-Jun, Rela, VDR, and C/EBPα were analyzed by Western blot in heart tissues from I/R mice (n = 4). cf The effects of c-Jun siRNA and Rela siRNA in OGDR-treated NRCMs as determined by TUNEL staining (c, e, n = 4) and Western blot (d, f, n = 6). Immunofluorescent staining for α-actinin was used to label cardiomyocytes. Scale bar = 100 μm (c, e). Data were expressed as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001

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