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Table 2 Detailed information and serological profiles of five children from Kimberley, South Africa, with serological evidence of current or previous infection with HBV (based on positive HBsAg (n = 3) and/or anti-HBc (n = 3))

From: HBV vaccination and PMTCT as elimination tools in the presence of HIV: insights from a clinical cohort and dynamic model

Subject ID

K306

K405

KReC51

KReC151

K093

Cohort

HIV+ age ≤ 60 months

HIV+ age ≤ 60 months

KReC

KReC

HIV+ age > 60 months

Sex

F

F

F

M

F

Age (months) at time of sampling

18

37

20

15

118

HIV infection

Positive

Positive

Negative

Negative

Positive

ARTa (if HIV positive)

Yes

Yes

n/a

n/a

No

Number of doses of HBV vaccine

NK

NK

NK

3

NK

HBsAg resultb

Detected

Detected

Detected

Not detected

Not detected

Anti-HBc resultc

Not detected

Not detected

Detected

Detected

Detected

HBeAg resultd

Not done

Not done

Detected

Not done

Not done

Anti-HBs resulte

Not detected

Not detected

Not detected

Detected

Not detected

Interpretation

Active infection

Active infection

Active infection

Immunised, infected and cleared

Infected and cleared

  1. aART indicates the participant was receiving anti-retroviral therapy to treat HIV infection; bhepatitis B surface antigen test; chepatitis B core antibody test; dhepatitis B envelope antigen test; ehepatitis B surface antibody test (vaccine mediated response). KReC Kimberley Respiratory Cohort, n/a not applicable, NK not known