Fig. 6

Temporal evolution of key epidemiologic indicators of HSV-1 infection in the total population of all ages of the US. a Estimated orally acquired HSV-1 seroprevalence versus genitally acquired HSV-1 seroprevalence. b Estimated orally acquired HSV-1 incidence rate versus genitally acquired HSV-1 incidence rate. c Estimated annual number of new (incident) orally acquired versus genitally acquired HSV-1 infections. Of note that the y-axis scales are different for the oral versus genital estimates