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Table 3 Multimorbidity, cancer and vascular mortality over 7-year median follow-up: Cox’s regression analysis

From: Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort

Cancer mortality

N = 500,769

7-year cumulative cancer mortality

Unadjusted number of events = 8350

Adjusted* (missing values n = 12,045; 2.4%); number of events = 8037

  

Hazard ratios (95% confidence intervals)

No LTC N = 172,593

1524 (0.88%)

1

1

1 LTC N = 163,705

2723 (1.66%)

1.56 (1.46–1.66)

1.50 (1.41–1.60)

2 LTC N = 95,226

2086 (2.19%)

1.80 (1.68–1.92)

1.66 (1.55–1.78)

3 LTC N = 43,120

1155 (2.67%)

2.04 (1.89–2.21)

1.79 (1.65–1.94)

≥ 4 LTC N = 26,125

862 (3.29%)

2.44 (2.25–2.66)

2.01 (1.84–2.20)

Vascular mortality

 

7-year cumulative vascular mortality

Unadjusted number of events = 2985

Adjusted* (missing values n = 12,045; 2.4%); number of events = 2799

  

Hazard ratios (95% confidence intervals) for vascular mortality

No LTC N = 172,593

429 (0.24%)

1

1

1 LTC N = 163,705

691 (0.42%)

1.41 (1.25–1.59)

1.31 (1.15–1.48)

2 LTC N = 95,226

729 (0.76%)

2.25 (1.99–2.54)

1.89 (1.67–2.14)

3 LTC N = 43,120

565 (1.3%)

3.58 (3.15–4.07)

2.74 (2.39–3.13)

≥ 4 LTC N = 26,125

571 (2.18%)

5.80 (5.11–6.59)

3.71 (3.23–4.27)

  1. Age as the time scale for both analyses. LTCs long-term conditions. *Adjusted for sex, socioeconomic status based on Townsend score, smoking status, alcohol status, body mass index and physical activity levels reported at baseline