Skip to main content

Table 3 Multimorbidity, cancer and vascular mortality over 7-year median follow-up: Cox’s regression analysis

From: Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort

Cancer mortality
N = 500,769 7-year cumulative cancer mortality Unadjusted number of events = 8350 Adjusted* (missing values n = 12,045; 2.4%); number of events = 8037
   Hazard ratios (95% confidence intervals)
No LTC N = 172,593 1524 (0.88%) 1 1
1 LTC N = 163,705 2723 (1.66%) 1.56 (1.46–1.66) 1.50 (1.41–1.60)
2 LTC N = 95,226 2086 (2.19%) 1.80 (1.68–1.92) 1.66 (1.55–1.78)
3 LTC N = 43,120 1155 (2.67%) 2.04 (1.89–2.21) 1.79 (1.65–1.94)
≥ 4 LTC N = 26,125 862 (3.29%) 2.44 (2.25–2.66) 2.01 (1.84–2.20)
Vascular mortality
  7-year cumulative vascular mortality Unadjusted number of events = 2985 Adjusted* (missing values n = 12,045; 2.4%); number of events = 2799
   Hazard ratios (95% confidence intervals) for vascular mortality
No LTC N = 172,593 429 (0.24%) 1 1
1 LTC N = 163,705 691 (0.42%) 1.41 (1.25–1.59) 1.31 (1.15–1.48)
2 LTC N = 95,226 729 (0.76%) 2.25 (1.99–2.54) 1.89 (1.67–2.14)
3 LTC N = 43,120 565 (1.3%) 3.58 (3.15–4.07) 2.74 (2.39–3.13)
≥ 4 LTC N = 26,125 571 (2.18%) 5.80 (5.11–6.59) 3.71 (3.23–4.27)
  1. Age as the time scale for both analyses. LTCs long-term conditions. *Adjusted for sex, socioeconomic status based on Townsend score, smoking status, alcohol status, body mass index and physical activity levels reported at baseline