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Table 6 Odds ratios (95% confidence intervals) of somatic diseases/disorders (lifetime prevalence) regressed on immune-mediated classes, men and women

From: A step beyond the hygiene hypothesis—immune-mediated classes determined in a population-based study

 

Neutral class

Resilient class

Atopic class

Mixed class

ACE class

Men

 Ulcer

1 (ref.)

1.6 (1.1–2.3)

1.0 (0.4–2.1)

0.7 (0.3–1.6)

0.7 (0.3–2.1)

 Irritable bowel syndrome

1 (ref.)

1.0 (0.5–2.1)

3.0 (1.3–7.0)

2.5 (1.1–5.6)

1.1 (0.3–4.8)

 Cystitis

1 (ref.)

0.7 (0.4–1.3)

3.2 (1.8–5.7)

3.3 (1.9–5.5)

1.5 (0.6–3.6)

 Acne

1 (ref.)

0.7 (0.5–1.1)

1.4 (0.8–2.5)

1.8 (1.1–2.8)

0.7 (0.3–1.7)

 Psoriasis

1 (ref.)

0.7 (0.4–1.1)

0.3 (0.1–1.2)

1.3 (0.7–2.5)

1.2 (0.5–2.9)

 Migraine

1 (ref.)

1.1 (0.7–1.6)

1.8 (1.1–3.2)

2.3 (1.5–3.6)

1.3 (0.6–2.6)

Women

 Ulcer

1 (ref.)

1.3 (0.8–2.1)

1.5 (0.8–2.9)

1.4 (0.8–2.5)

3.1 (1.8–5.4)

 Irritable bowel syndrome

1 (ref.)

1.5 (0.9–2.4)

2.0 (1.1–3.8)

2.9 (1.8–4.8)

3.7 (2.1–6.6)

 Cystitis

1 (ref.)

1.0 (0.8–1.2)

2.1 (1.5–2.8)

1.9 (1.5–2.5)

2.2 (1.5–3.0)

 Acne

1 (ref.)

0.9 (0.6–1.3)

1.1 (0.6–1.7)

1.5 (1.0–2.2)

1.8 (1.1–2.8)

 Psoriasis

1 (ref.)

0.9 (0.5–1.5)

1.0 (0.5–2.1)

0.9 (0.5–1.8)

1.6 (0.8–3.2)

 Migraine

1 (ref.)

0.9 (0.7–1.2)

1.7 (1.2–2.4)

1.2 (0.9–1.7)

1.2 (0.8–1.8)

  1. ACE adverse childhood experiences