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Table 4 Mortality rates in the RIACE participants with valid information on vital status, stratified by BP status according to the 130/80 mmHg or 140/90 mmHg BP targets

From: Is resistant hypertension an independent predictor of all-cause mortality in individuals with type 2 diabetes? A prospective cohort study

  N Events Percent events Events per 1000 patient-years (95% CI) unadjusted P Events per 1000 patient-years (95% CI) age- and gender-adjusted P
Study groups
130/80 mmHg BP targets   < 0.0001   < 0.0001
NT 2206 316 14.32 18.36 (16.33–20.38)   10.15 (8.64–11.92)  
UTHT 2378 380 15.98 20.65 (18.57–22.73)   9.52 (8.17–11.10)  
CHT 3707 980 26.44 36.67 (34.37–38.96)   14.39 (12.61–16.41)  
UCHT 5014 1180 23.53 31.76 (29.94–33.57)   11.93 (10.50–13.55)  
RHT 2351 746 31.73 44.94 (41.72–48.17)   15.68 (13.70–17.94)  
CRHT 305 107 35.08 50.93 (41.28–60.58)   20.36 (16.34–25.38)  
UCRHT 2046 639 31.23 44.08 (40.66–47.49)   15.07 (13.13–17.30)  
140/90 mmHg BP targets   < 0.0001   < 0.0001
NT 3445 492 14.28 18.31 (16.69–19.93)   9.72 (8.39–11.26)  
UTHT 1139 204 17.91 23.31 (20.11–26.51)   9.86 (8.24–11.80)  
CHT 6298 1619 25.71 35.44 (33.72–37.17)   13.61 (12.01–15.43)  
UCHT 2952 707 23.95 32.26 (29.88–34.64)   11.82 (10.32–13.53)  
RHT 1882 580 31.83 43.56 (40.01–47.10)   15.82 (13.76–18.18)  
CRHT 559 173 30.95 43.93 (37.38–50.47)   17.15 (14.23–20.67)  
UCRHT 1263 407 32.22 45.46 (41.04–49.88)   15.31 (13.18–17.77)  
  1. RIACE Renal Insufficiency And Cardiovascular Events, BP blood pressure, CI confidence interval; NT normotension, UTHT untreated hypertension, CHT controlled hypertension (on-target with 1, 2, or 3 drugs), UCHT uncontrolled hypertension (not on-target with 1 or 2 drugs), RHT resistant hypertension (on-target with > 4 drugs or not on-target with > 3 drugs), CRHT controlled resistant hypertension (on-target with > 4 drugs), UCRHT uncontrolled resistant hypertension (not on-target with > 3 drugs)