Skip to main content

Advertisement

Table 2 Baseline characteristics of participants by study type

From: Three randomized controlled trials evaluating the impact of “spin” in health news stories reporting studies of pharmacologic treatments on patients’/caregivers’ interpretation of treatment benefit

 Preclinical studyPhase I/II non-randomized trialPhase III/IV RCT
Spin (N = 150)No spin* (N = 150)Total (N = 299)Spin (N = 150)No spin (N = 150)Total (N = 300)Spin (N = 150)No spin (N = 150)Total (N = 300)
Participants
 Patient142 (94.6%)138 (92.6%)280 (93.7%)134 (89.3%)136 (90.7%)270 (90%)135 (90%)137 (91.3%)272 (90.7%)
 Caregiver4 (2.7%)5 (3.4%)9 (3.0%)9 (6.0%)8 (5.3%)17 (5.7%)10 (6.7%)9 (6.0%)19 (6.3%)
 Others4 (2.7%)6 (4.0%)10 (3.3%)7 (4.7%)6 (4.0%)13 (4.3%)5 (3.3%)4 (2.7%)9 (3.0%)
Age
 18–291 (0.7%)5 (3.4%)6 (2.0%)5 (3.3%)2 (1.3%)7 (2.3%)2 (1.3%)3 (2.0%)5 (1.6%)
 30–4926 (17.3%)24 (16.1%)50 (16.7%)20 (13.3%)22 (14.7%)42 (14.0%)29 (19.4%)27 (18.0%)56 (18.7%)
 50–6988 (58.7%)90 (60.4%)178 (59.5%)95 (63.4%)90 (60.0%)185 (61.7%)102 (68.0%)90 (60.0%)192 (64.0%)
 ≥ 7035 (23.3%)30 (20.1%)65 (21.7%)30 (20.0%)36 (24.0%)66 (22.0%)17 (11.3%)30 (20.0%)47 (15.7%)
Sex (female)123 (82.0%)119 (79.9%)242 (80.9%)143 (95.3%)134 (89.3%)277 (92.3%)120 (80.0%)125 (83.3%)245 (81.7%)
Frequency of reading news stories
 Never1 (0.7%)3 (2.0%)4 (1.3%)0 (0.0%)1 (0.7%)1 (0.3%)1 (0.7%)1 (0.7%)2 (0.7%)
 1/month4 (2.7%)4 (2.7%)8 (2.7%)9 (6.0%)9 (6.0%)18 (6.0%)4 (2.7%)2 (1.3%)6 (2.0%)
 1/week14 (9.3%)17 (11.4%)31 (10.4%)21 (14.0%)10 (6.7%)31 (10.3%)15 (10.0%)20 (13.3%)35 (11.7%)
 Daily131 (87.3%)125 (83.9%)256 (85.6%)120 (80.0%)130 (86.6%)250 (83.4%)130 (86.6%)127 (84.7%)257 (85.6%)
Rely on health news stories to make decisions about health86 (57.3%)80 (53.7%)166 (55.5%)88 (58.7%)98 (65.3%)186 (62.0%)89 (59.3%)83 (55.3%)172 (57.3%)
Primary source of information about new treatments
 Online health news62 (41.3%)62 (41.6%)124 (41.5%)76 (50.7%)68 (45.3%)144 (48.0%)65 (43.3%)55 (36.7%)120 (40.0%)
 Physicians63 (42.0%)59 (39.6%)122 (40.8%)44 (29.3%)50 (33.3%)94 (31.3%)55 (36.7%)62 (41.3%)117 (39.0%)
 Family or friends1 (0.7%)1 (0.7%)2 (0.7%)4 (2.7%)2 (1.4%)6 (2.0%)3 (2.0%)1 (0.7%)4 (1.3%)
 Television1 (0.7%)2 (1.3%)3 (1.0%)1 (0.7%)0 (0.0%)1 (0.3%)1 (0.7%)4 (2.7%)5 (1.7%)
 Social media7 (4.7%)8 (5.4%)15 (5.0%)8 (5.3%)6 (4.0%)14 (4.7%)12 (8.0%)6 (4.0%)18 (6.0%)
 Others16 (10.6%)17 (11.4%)33 (11.0%)17 (11.3%)24 (16.0%)41 (13.7%)14 (9.3%)22 (14.6%)36 (12.0%)
  1. RCT randomized controlled trial
  2. *The baseline data were missing for one participant