| |
Severe malarial anemia (n = 219)
|
Cerebral malaria (n = 260)
|
|---|
|
No AKI (n = 164)
|
AKI (n = 55)
|
p value
|
No AKI (n = 147)
|
AKI (n = 113)
|
p value
|
|---|
|
Supportive care
|
|
Oxygen
|
22 (6.7)
|
7 (12.7)
|
0.160
|
71 (48.3)
|
76 (67.3)
|
0.002
|
|
Antipyretics
|
161 (98.2)
|
53 (96.4)
|
0.437
|
138 (93.9)
|
104 (92.0)
|
0.562
|
|
Medications
|
|
Quinine
|
127 (77.4)
|
44 (80.0)
|
0.691
|
131 (89.1)
|
99 (87.6)
|
0.707
|
|
Artesunate/artemether
|
55 (33.5)
|
16 (29.1)
|
0.619
|
43 (29.3)
|
39 (34.5)
|
0.420
|
|
Anticonvulsants
|
1 (0.6)
|
2 (3.6)
|
0.156
|
109 (74.2)
|
96 (85.0)
|
0.034
|
|
Furosemide
|
32 (19.5)
|
11 (20.0)
|
0.937
|
9 (6.1)
|
26 (23.0)
|
< 0.0001
|
|
Bolus dextrose
|
28 (17.1)
|
28 (50.9)
|
< 0.0001
|
132 (89.8)
|
91 (80.5)
|
0.034
|
|
Intravenous fluids
|
12 (7.3)
|
5 (9.1)
|
0.671
|
24 (16.3)
|
32 (28.3)
|
0.020
|
|
0.9% saline
|
10 (6.1)
|
4 (7.3)
|
0.754
|
18 (12.2)
|
24 (21.2)
|
0.051
|
|
Ringer’s lactate
|
0 (0.0)
|
0 (0.0)
|
–
|
2 (1.4)
|
4 (3.5)
|
0.246
|
|
10% dextrose
|
0 (0.0)
|
0 (0.0)
|
–
|
4 (2.7)
|
2 (1.8)
|
0.700
|
|
Bicarbonate
|
0 (0.0)
|
0 (0.0)
|
–
|
0 (0.0)
|
1 (0.9)
|
0.435
|
|
Darrow’s
|
0 (0.0)
|
1 (1.8)
|
0.251
|
1 (0.7)
|
0 (0.0)
|
1.000
|
|
Albumin
|
2 (1.2)
|
0 (0.0)
|
1.000
|
2 (1.4)
|
4 (3.5)
|
0.408
|
|
Blood transfusion
|
164 (100.0)
|
55 (100.0)
|
–
|
68 (46.3)
|
81 (71.7)
|
< 0.0001
|
- Data presented as n (%) and compared using Pearson’s chi-square or Fisher’s exact, as appropriate
