Skip to main content

Table 2 Cases of malaria detected per type of diagnostic, for all included patients (n = 916)

From: The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study

  Total Children Adults
All ages 0–2 years 2–5 years 5–15 years > 15 years
n = 908 n = 266 n = 180 n = 127 n = 335
n (%) n (%) n (%) n (%) n (%)
Microscopy 240 (26.4) 88 (33.1) 75 (41.7) 36 (28.1) 41 (12.3)
RDT (minimal 1 test positive) 396 (43.6) 131 (49.3) 118 (65.6) 68 (53.1) 79 (23.7)
 Both positive 212 (53.3) 86 (65.7) 68 (57.6) 30 (44.1) 28 (35.0)
 Only HRP2 positive 175 (44.2) 44 (33.6) 49 (41.5) 35 (52.2) 47 (59.5)
 Only pLDH positive 9 (2.3) 1 (0.8) 1 (0.9) 2 (2.9) 5 (6.3)
qPCR1 374 (41.2) 118 (44.4) 104 (57.8) 58 (45.3) 94 (28.1)
 > 20 p/μL 218 (24.1) 84 (31.6) 75 (41.7) 29 (22.7) 30 (8.9)
 > 1 and < 20 p/μL 74 (8.2) 14 (5.3) 12 (6.7) 18 (14.0) 30 (8.9)
 > 0.05 and < 1 p/μL 81 (8.9) 20 (7.5) 17 (9.4) 11 (8.6) 33 (9.9)
XN-302,3 255 (28.0) 87 (32.7) 79 (43.9) 39 (30.7) 50 (14.9)
  1. 1Excluding six false negative PCRs, which were most likely false negative due to sample mix-up
  2. 2Excluding 71 patients with an abnormal scattergram, three of whom had positive malaria microscopy
  3. 3There were three false negative cases detected by microscopy but not detected by XN-30