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Table 3 Diagnostic accuracy of XN-30 compared to malaria microscopy. Data with and without correction for qPCR confirmed sub-microscopic parasitemia cases

From: The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study

 

XN-30, uncorrected (n = 837)

XN-30, corrected* (n = 837)

 

Positive

Negative

Positive

Negative

Positive microscopy

234

3

253

3

Negative microscopy

21

579

2

579

Sensitivity

98.7%

 

98.8%

 

Specificity

96.5%

 

99.7%

 

PPV

91.8%

 

99.2%

 

NPV

99.5%

 

99.5%

 

ROC

0.98

 

0.99

 
  1. *In case of incongruent results between malaria microscopy and XN-30, the microscopy data was adjusted to the PCR result