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Fig. 2 | BMC Medicine

Fig. 2

From: Tissue-infiltrating lymphocytes signature predicts survival in patients with early/intermediate stage hepatocellular carcinoma

Fig. 2

ROC curves of overall survival (OS) for the ICPI and other 7 staging systems in the training (a) and validation (b) cohorts. The C-index value of the ICPI model for OS was significantly higher than those for the Okuda, CLIP, LCSGJ, JIS, AJCC 7th edition, AJCC 8th edition, and BCLC classifications for OS [0.691 vs 0.548 (P < 0.001), 0.597 (P < 0.001), 0.557 (P < 0.001), 0.553 (P < 0.001), 0.595 (P = 0.008), 0.589 (P = 0.002), 0.552 (P < 0.001), respectively] in the training cohort. The validation cohort shared the similar trend [ICPI vs Okuda 0.686 vs 0.602 (P < 0.001), CLIP 0.610 (P = 0.01), LCSGJ 0.553 (P < 0.001), JIS 0.556 (P < 0.001), AJCC 7th edition 0.519 (P < 0.001), AJCC 8th edition 0.573 (P < 0.001), BCLC 0.544 (P < 0.001), respectively]

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