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Table 1 Trial treatment arms

From: Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration

Age WHO Plan C Slow arm
No shock With WHO shock* No shock With shock
< 12 months Step 1
30 ml/kg over 1 h
Step 2
70 ml/kg over 5 h
Resuscitate:
Up to 3 × 20 ml/kg bolus then to step 2
70 ml/kg over 5 h
100 ml/kg over 8 h 100 ml/kg over 8 h with
No additional boluses
> 12 months Step 1
30 ml/kg over 30 min
Step 2
70 ml/kg over 2.5 h
Resuscitate:
Up to 3 × 20 ml/kg bolus then to step 2
70 ml/kg over 2.5 h
100 ml/kg over 8 h 100 ml/kg over 8 h
No additional boluses
  1. *Shock defined as presence of all three of the following: Weak and fast pulse, temperature gradient and prolonged capillary refill time > 3 s (10)