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Table 2 Baseline characteristics

From: Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration

  WHO plan C GASTRO slow Total
Female, n (%) 23 (38) 27 (44) 50 (41)
Age (months), median (IQR) 9 (6–12) 8 (6–12) 8 (6–12)
Weight (kg), median (IQR) 7.7 (6.8, 8.3) 7.3 (6.8,8.3) 7.5 (6.7–8.3)
Axillary temperature (°C), median (IQR) 37.6 (37.0, 38.2) 37.8 (37.2, 38.3) 37.7 (37.0, 38.2)
 < 36, n (%) 1 (2) 1 (2) 2 (2)
 > 37.5, n (%) 32 (52) 37 (61) 69 (57)
Sunken eyes, n (%)
 Slightly sunken 17 (28) 18 (30) 35 (29)
 Very sunken 44 (72) 42 (69) 86 (70)
Decreased skin turgora, n (%) 32 (52) 34 (56) 66 (54)
Heart rate, median (IQR) 145.0 (138.5, 159.0) 149.5 (140.5, 160.5) 148 (139, 160)
 Bradycardia (< 80 bpm), n (%) 0 (0) 0 (0) 0 (0)
 Severe tachycardiab, n (%) 7 (11) 11 (18) 18 (15)
Systolic blood pressure, median (IQR) 90 (85, 95) 89 (85, 96.5) 89 (85, 96)
 Moderate hypotension, n (%)c 2 (3) 5 (8) 7 (6)
 Severe hypotension, n (%)d 1 (2) 0 (0) 1 (1)
Capillary refill time, median (IQR) 1 (1, 1) 1 (1, 1) 1 (1, 1)
 ≥ 3, n (%) 5 (8) 3 (5) 8 (7)
No. with weak pulse, n (%) 6 (10) 7 (11) 13 (11)
No. with temperature gradient, n (%) 11 (18) 10 (16) 21 (17)
Respiratory rate, median (IQR) 40 (37, 48) 44 (40, 50) 43 (38, 49)
 Fast breathing, n (%) 2 (3) 3 (5) 5 (4)
Respiratory distress, n (%) 5 (8) 9 (15) 14 (11)
Oxygen saturation, median (IQR) 98 (97, 99) 98 (97, 98) 98 (97, 99)
Conscious level, n (%)
 Alert 12 (20) 16 (26) 28 (23)
 Lethargic 35 (57) 30 (49) 65 (53)
 Prostrate 13 (21) 13 (21) 26 (21)
 Coma 1 (2) 2 (3) 3 (2)
No. with fits or convulsions, n (%) 1 (2) 0 (0) 1 (1)
  1. aRecoil from skin pinch > 2 s
  2. bDefined as heart rate > 180 for age < 12 months; > 160 for age 12–60 months; > 140 for age ≥ 60 months
  3. cModerate Hypotension defined as: if < 12 months = 50-75 mmHg; 12 months to 5 yrs = 60-75 mmHg; > 5 yrs = 70-85mmHg
  4. dSevere hypotension defined as: if < 12 months ≤ 50mmHg; 12 months to 5 yrs ≤ 60mmHg, > 5 yrs ≤ 70mmHg