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Table 2 Baseline characteristics

From: Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration

 

WHO plan C

GASTRO slow

Total

Female, n (%)

23 (38)

27 (44)

50 (41)

Age (months), median (IQR)

9 (6–12)

8 (6–12)

8 (6–12)

Weight (kg), median (IQR)

7.7 (6.8, 8.3)

7.3 (6.8,8.3)

7.5 (6.7–8.3)

Axillary temperature (°C), median (IQR)

37.6 (37.0, 38.2)

37.8 (37.2, 38.3)

37.7 (37.0, 38.2)

 < 36, n (%)

1 (2)

1 (2)

2 (2)

 > 37.5, n (%)

32 (52)

37 (61)

69 (57)

Sunken eyes, n (%)

 Slightly sunken

17 (28)

18 (30)

35 (29)

 Very sunken

44 (72)

42 (69)

86 (70)

Decreased skin turgora, n (%)

32 (52)

34 (56)

66 (54)

Heart rate, median (IQR)

145.0 (138.5, 159.0)

149.5 (140.5, 160.5)

148 (139, 160)

 Bradycardia (< 80 bpm), n (%)

0 (0)

0 (0)

0 (0)

 Severe tachycardiab, n (%)

7 (11)

11 (18)

18 (15)

Systolic blood pressure, median (IQR)

90 (85, 95)

89 (85, 96.5)

89 (85, 96)

 Moderate hypotension, n (%)c

2 (3)

5 (8)

7 (6)

 Severe hypotension, n (%)d

1 (2)

0 (0)

1 (1)

Capillary refill time, median (IQR)

1 (1, 1)

1 (1, 1)

1 (1, 1)

 ≥ 3, n (%)

5 (8)

3 (5)

8 (7)

No. with weak pulse, n (%)

6 (10)

7 (11)

13 (11)

No. with temperature gradient, n (%)

11 (18)

10 (16)

21 (17)

Respiratory rate, median (IQR)

40 (37, 48)

44 (40, 50)

43 (38, 49)

 Fast breathing, n (%)

2 (3)

3 (5)

5 (4)

Respiratory distress, n (%)

5 (8)

9 (15)

14 (11)

Oxygen saturation, median (IQR)

98 (97, 99)

98 (97, 98)

98 (97, 99)

Conscious level, n (%)

 Alert

12 (20)

16 (26)

28 (23)

 Lethargic

35 (57)

30 (49)

65 (53)

 Prostrate

13 (21)

13 (21)

26 (21)

 Coma

1 (2)

2 (3)

3 (2)

No. with fits or convulsions, n (%)

1 (2)

0 (0)

1 (1)

  1. aRecoil from skin pinch > 2 s
  2. bDefined as heart rate > 180 for age < 12 months; > 160 for age 12–60 months; > 140 for age ≥ 60 months
  3. cModerate Hypotension defined as: if < 12 months = 50-75 mmHg; 12 months to 5 yrs = 60-75 mmHg; > 5 yrs = 70-85mmHg
  4. dSevere hypotension defined as: if < 12 months ≤ 50mmHg; 12 months to 5 yrs ≤ 60mmHg, > 5 yrs ≤ 70mmHg