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Table 3 Admission, 8 hour and 24 hour biochemistry

From: Gastroenteritis aggressive versus slow treatment for rehydration (GASTRO): a phase II rehydration trial for severe dehydration: WHO plan C versus slow rehydration

  Plan C GASTRO slow Total
Admission laboratory
N 53 50 103
  Sodium, median (IQR) 139 (132, 149) 143 (137, 156) 142 (136, 154)
   Hyponatremia (< 135 mmol/L), n (%) 16 (30) 8 (16) 24 (23)
   Hypernatremia (> 145 mmol/L), n (%) 15 (28) 23 (46) 38 (37)
   Severe hypernatraemia > 150 mol/L, n (%) 11 (21) 16 (32) 27 (26)
   Hypokalaemia (< 3.5 mmol/L), n (%) 11 (21) 8 (16) 19 (18)
   High creatinine (> 74 mmol/L), n (%) 11 (21) 12 (24) 23 (23)
   High urea (> 6.4 mmol/L), n (%) 26 (49) 26 (52) 52 (50)
  Glucose, median (IQR) 5.4 (4.9, 6.3) 5.3 (4.4, 6.9) 5.4 (4.7, 6.8)
  Lactatea, median (IQR); N 1.2 (1.0, 2.1); 29 1.3 (1.1, 1.7); 27 1.3 (1.0, 1.7); 56
   High lactate > 3 mmol/l, n (%) 4 (14) 0 (0) 4 (7)
At 8 hours
N 50 52 102
  Sodium, median (IQR) 142 (135, 147) 142 (138, 148) 142 (136, 148)
   Hyponatremia (< 135 mmol/L), n (%) 12 (24) 6 (12) 18 (18)
   Hypernatremia (> 145 mmol/L), n (%) 17 (34) 19 (37) 36 (35)
   Severe hypernatraemia > 150 mol/L, n (%) 7 (14) 10 (19) 17 (17)
At 24 hours
N 41 45 86
  Sodium, median (IQR) 142 (138, 154) 143 (138, 156) 143 (138, 155)
   Hyponatremia (< 135 mmol/L), n (%) 7 (17) 5 (11) 12 (14)
   Hypernatremia (> 145 mmol/L), n (%) 16 (39) 18 (40) 34 (40)
   Severe hypernatraemia > 150 mol/L, n (%) 12 (29) 16 (36) 28 (33)
  1. aSoroti sites were unable to do lactate tests