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Table 2 Diagnostic test accuracy of the 4AT the CAM for diagnosis of delirium (defined by reference standard assessment)

From: Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method

  Sensitivity Specificity Positive predictive value Negative predictive value Youden’s Index
4AT (> 3), n (95% CI) 76% (61 to 87%) 94% (92 to 97%) 66% (52 to 78%) 96% (94 to 98%) 0.70
CAM Positive, n (95% CI) 40% (26 to 57%) 100% (98 to 100%) 94% (73 to 100%) 93% (90 to 96%) 0.40
Difference in Proportions 36% (15 to 53%) − 6% (− 14 to 2%) − 28% (− 53 to − 2%) 3% (− 4 to 11%)  
p value 0.0012 < 0.0001 0.0297 0.0629  
  1. Numbers are estimates (95% CI). Youden’s Index is equal to sensitivity + specificity − 1, a value of zero indicates no value, and a value of 1 indicates a perfect test. The difference in proportions is 4AT-CAM for each of the tabulated measures of diagnostic accuracy, accompanied by the corresponding p value from Fisher’s exact test comparing proportions
  2. CI confidence interval, PPV positive predictive value, NPV negative predictive value