Delirium detection in older acute medical inpatients: a multicentre prospective comparative diagnostic test accuracy study of the 4AT and the confusion assessment method

Table 2 Diagnostic test accuracy of the 4AT the CAM for diagnosis of delirium (defined by reference standard assessment)

	Sensitivity	Specificity	Positive predictive value	Negative predictive value	Youden’s Index
4AT (> 3), n (95% CI)	76% (61 to 87%)	94% (92 to 97%)	66% (52 to 78%)	96% (94 to 98%)	0.70
CAM Positive, n (95% CI)	40% (26 to 57%)	100% (98 to 100%)	94% (73 to 100%)	93% (90 to 96%)	0.40
Difference in Proportions	36% (15 to 53%)	− 6% (− 14 to 2%)	− 28% (− 53 to − 2%)	3% (− 4 to 11%)
p value	0.0012	< 0.0001	0.0297	0.0629

Numbers are estimates (95% CI). Youden’s Index is equal to sensitivity + specificity − 1, a value of zero indicates no value, and a value of 1 indicates a perfect test. The difference in proportions is 4AT-CAM for each of the tabulated measures of diagnostic accuracy, accompanied by the corresponding p value from Fisher’s exact test comparing proportions
CI confidence interval, PPV positive predictive value, NPV negative predictive value

ISSN: 1741-7015