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Table 1 CVD incidence and baseline characteristics of the entire study population

From: The uncertainty with using risk prediction models for individual decision making: an exemplar cohort study examining the prediction of cardiovascular disease in English primary care

  CPRD female N = 1,965,078 CPRD male N = 1,890,582
Outcome variables
 Incident CVD cases 86,547 107,051
 Person years 13,801,919 12,977,235
 Rate per 1000 person-years 6.27 8.24
Demographics
 Age 43.07 (15.94) 41.84 (14.57)
 Ethnicity   
  Recorded 42.07% 38.21%
  White/not recorded 94.12% 94.48%
  Indian 1.14% 1.19%
  Pakistani 0.45% 0.49%
  Bangladeshi 0.14% 0.19%
  Other Asian 0.84% 0.78%
  Black 1.73% 1.52%
  Chinese 0.33% 0.23%
  Other 1.27% 1.12%
Test data
 BMI 25.60 (5.60) 26.12 (4.54)
 Cholesterol/HDL ratio 3.72 (1.20) 4.48 (1.40)
 SBP 123.91 (18.28) 130.03 (16.48)
 SBP variability 9.47 (5.98) 10.13 (6.80)
 Smoking status Never = 56.04%, Ex = 16.97%, Current = 26.99% Never = 46.63%, Ex = 17.48%, Current = 35.99%
Medical history
 Atrial fibrillation 0.44% 0.57%
 Atypical antipsychotic medication use 0.30% 0.33%
 Chronic kidney disease   
  Stage 3/4/5 0.45% 0.32%
  Stage 4/5 0.12% 0.15%
 Corticosteroid use 0.48% 0.30%
 Erectile dysfunction NA 1.45%
 Family history of CVD 15.08% 11.02%
 HIV/AIDS 0.06% 0.09%
 Migraine 7.27% 2.94%
 Rheumatoid arthritis 0.69% 0.26%
 Severe mental illness 8.63% 4.59%
 Systemic lupus erythematosus 0.10% 0.01%
 Treated hypertension 6.18% 4.50%
 Type 1 diabetes 0.21% 0.28%
 Type 2 diabetes 1.16% 1.42%
Variables not in QRISK
 Number medical records in the previous year 14.94 (13.97) 8.83 (11.45)
 > 50 medical records in the previous year 2.84% 1.37%
 Number of prescription items in the previous year 9.60 (19.87) 5.72 (16.00)
 Number with > 50 prescription items in the previous year 3.49% 2.04%
 Alcohol abuse 0.65% 1.46%
 Anxiety 13.44% 7.96%
 Left ventricular hypertrophy 0.14% 0.18%
 Region   
  North East 1.89% 1.96%
  North west 13.10% 13.38%
  Yorkshire and the Humber 3.93% 3.85%
  East Midlands 3.14% 3.23%
  West Midlands 11.04% 11.28%
  East of England 11.67% 11.68%
  South west 11.99% 11.88%
  South Central 12.84% 12.81%
  London 17.52% 17.18%
  South East Coast 12.88% 12.74%
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